TumorDet: A Breast Tumor Detection Model Based on Transfer Learning and ShuffleNet

IF 2.4 3区 生物学 Q3 BIOCHEMICAL RESEARCH METHODS Current Bioinformatics Pub Date : 2023-08-15 DOI:10.2174/1574893618666230815121150
Leying Pan, T. Zhang, Qiang Yang, Guoping Yang, Nan Han, Shaojie Qiao
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Abstract

Breast tumor is among the most malignant tumors and early detection can improve patient’s survival rate. Currently, mammography is the most reliable method for diagnosing breast tumor because of high image resolution. Because of the rapid development of medical and artificial intelligence techniques, computer-aided diagnosis technology can greatly improve the detection accuracy of breast tumors and medical imaging has begun to use deep-learning-based approaches. In this study, the TumorDet model is proposed to detect the benign and malignant lesions of breast tumor, which has positive significance for assisting doctors in diagnosis. We use the proposed TumorDet to analyze and predict breast tumors on the real MRI dataset. (1) We introduce an adaptive gamma correction (AGC) method to balance brightness equalization and increase the contrast of mammography images; (2) we use the ShuffleNet model to exchange information between different feature layers and extract the hidden high-level features of medical images; and (3) we use the transfer learning method to fine-tune the ShuffleNet model and obtain the optimal parameters. The proposed TumorDet model has shown that accuracy, sensitivity, and specificity reach 90.43%, 89.37%, and 87.81%, respectively. TumorDet performs well in the breast tumor detection task. In addition, we use the proposed TumorDet to conduct experiments on other tasks, such as forest fires, and the robustness of TumorDet is proved by experimental results. TumorDet employs the ShuffleNet model to exchange information between different feature layers without increasing the number of network parameters and applies transfer learning methods to further extract the basic features of medical images by fine-tuning. The model is beneficial for the localization and classification of breast tumors and also performs well in forest fire detection.
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肿瘤检测:一种基于迁移学习和ShuffleNet的乳腺肿瘤检测模型
乳腺肿瘤是最恶性的肿瘤之一,早期发现可以提高患者的生存率。目前,乳房X光检查由于图像分辨率高,是诊断乳腺肿瘤最可靠的方法。由于医学和人工智能技术的快速发展,计算机辅助诊断技术可以大大提高乳腺肿瘤的检测精度,医学成像已经开始使用基于深度学习的方法。本研究提出了肿瘤Det模型来检测乳腺肿瘤的良恶性病变,对协助医生诊断具有积极意义。我们使用所提出的肿瘤Det在真实的MRI数据集上分析和预测乳腺肿瘤。(1) 我们介绍了一种自适应伽马校正(AGC)方法,以平衡亮度均衡并提高乳房X光摄影图像的对比度;(2) 我们使用ShuffleNet模型在不同的特征层之间交换信息,提取医学图像的隐藏高级特征;(3)利用迁移学习方法对ShuffleNet模型进行微调,得到最优参数。所提出的肿瘤检测模型的准确性、敏感性和特异性分别达到90.43%、89.37%和87.81%。肿瘤Det在乳腺肿瘤检测任务中表现良好。此外,我们使用所提出的TumorDet对森林火灾等其他任务进行了实验,实验结果证明了TumorDet的稳健性。TumorDet采用ShuffleNet模型在不增加网络参数数量的情况下在不同特征层之间交换信息,并应用迁移学习方法通过微调进一步提取医学图像的基本特征。该模型有利于乳腺肿瘤的定位和分类,在森林火灾探测中也表现良好。
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来源期刊
Current Bioinformatics
Current Bioinformatics 生物-生化研究方法
CiteScore
6.60
自引率
2.50%
发文量
77
审稿时长
>12 weeks
期刊介绍: Current Bioinformatics aims to publish all the latest and outstanding developments in bioinformatics. Each issue contains a series of timely, in-depth/mini-reviews, research papers and guest edited thematic issues written by leaders in the field, covering a wide range of the integration of biology with computer and information science. The journal focuses on advances in computational molecular/structural biology, encompassing areas such as computing in biomedicine and genomics, computational proteomics and systems biology, and metabolic pathway engineering. Developments in these fields have direct implications on key issues related to health care, medicine, genetic disorders, development of agricultural products, renewable energy, environmental protection, etc.
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