Pharmacology: Spina Bifida and Urinary Tract Infection Management

Abstract

: Spinabifidaisoneof thecongenitalneuraltubedefects that can lead to loss of bladder control, also known as neurogenic blad- der. This can lead to recurrent urinary tract infections and subsequent renal function decline if not properly managed. Proper management mayincludepharmacologicalcarethataimstopreventimproperdrain-age of the bladder directly by utilizing agents such as anticholinergics, urinary antispasmodics, and botulism toxins. In addition to direct care, patients with neurogenic bladder also may require bowel regimens be- cause of concurrent instances of neurogenic bowels.