A Preliminary Look at the Macrovascular System for Transmetatarsal Amputation Success.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-11-01 DOI:10.1097/ASW.0000000000000057
Elizabeth Ansert, John Najjar, Robert J Snyder
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Abstract

ABSTRACT OBJECTIVE Transmetatarsal amputation (TMA) is a commonly used level of amputation that preserves most of the foot’s function and independence. However, many TMAs fail, and patients go onto higher amputations. The primary endpoint of this study is to determine if source artery occlusions are correlated with TMA flap failure. METHODS A total of 82 patients with TMAs were retrospectively reviewed for healing rates between 2009 and 2019 at a single center. Forty-five of the patients had an angiogram, which was analyzed for source artery and overall TMA failure. Of the initial 82 patients, a cohort of 12 had documentation of specific flap failure and an angiogram performed. This cohort of 12 patients was used for correlation of flap failure with source artery occlusion. RESULTS Overall, the TMA healing rate was 45.28%. No correlation was noted between a specific source artery occlusion and overall TMA failure. However, a moderate positive correlation was seen with dorsalis pedis artery and peroneal artery occlusions and dorsal flap failure. No correlation was seen with the posterior tibial artery and plantar flap failure. A moderate negative correlation was seen with peroneal artery occlusion and plantar flap failure. CONCLUSIONS The authors concluded that retrograde flow through the angiosome principle is what allowed for successful outcomes in TMAs. Physicians are urged to carefully plan, dissect, and preserve these vessels to help prevent TMA flap failure, especially in patients with vascular risk or disease.
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大血管系统对跖骨截肢成功的初步观察。
目的:跖骨切断术(TMA)是一种常用的截肢术,可保留足部的大部分功能和独立性。然而,许多TMA失败了,患者会接受更高级别的截肢手术。本研究的主要终点是确定源动脉闭塞是否与TMA皮瓣失效相关。方法:对2009年至2019年间在一个中心共82例TMAs患者的治愈率进行回顾性审查。45名患者进行了血管造影,分析了源动脉和总TMA衰竭。在最初的82名患者中,有12名患者记录了特定的皮瓣失败并进行了血管造影。这个由12名患者组成的队列用于研究皮瓣失效与源动脉闭塞的相关性。结果:总的来说,TMA的治愈率为45.28%。特定来源的动脉闭塞与总的TMA失败之间没有相关性。然而,足背动脉和腓动脉闭塞和背侧皮瓣失效之间存在中度正相关。胫骨后动脉和足底皮瓣失效之间没有相关性。腓动脉闭塞和足底皮瓣失效呈中度负相关。结论:作者得出结论,通过血管组原理的逆行是TMAs成功治疗的原因。医生被敦促仔细规划、解剖和保存这些血管,以帮助预防TMA皮瓣失败,尤其是在有血管风险或疾病的患者中。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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