The treatment challenge of heterotopic ossification in a patient with Parkinson's disease and stroke.

IF 1.7 4区 医学 Q4 NEUROSCIENCES International Journal of Neuroscience Pub Date : 2024-12-01 Epub Date: 2023-10-26 DOI:10.1080/00207454.2023.2273774
Ayşe Merve Ata, Bilge Kesikburun, Bedriye Başkan, Ebru Alemdaroğlu
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Abstract

Objective: Neurogenic heterotopic ossification (HO) is characterized by bone formation in a non-anatomical site. It is usually seen in patients with spinal cord injury and traumatic brain injury. It occurs less frequently in other types of acquired brain injury. Neurogenic HO has only been recorded in a few cases of Parkinson's disease (PD). Its treatment is challenging and may need pain palliation methods. The course and treatment approach of a complicated case with PD and stroke who developed HO of the hip joints during rehabilitation was discussed in this article.

Case presentation: A 79-year-old male patient with stroke and PD experienced restriction and pain in both hip joints. Bilateral HO was discovered on a pelvic radiograph. He did not benefit from exercises, transcutaneous electrical nerve stimulation, or indomethacin. Radiotherapy has also been tried to treat HO. Following that, obturator and femoral nerve blocks were used to relieve pain, and pain was reduced and sitting balance improved.

Conclusion: HO is a rare complication of PD and stroke that has an adverse effect on the rehabilitation process. Since treatment choices are limited, palliative pain management approaches such as peripheral nerve block may be considered.

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帕金森病和中风患者异位骨化的治疗挑战。
神经源性异位骨化(HO)的特点是在非解剖部位形成骨。它通常见于脊髓损伤和创伤性脑损伤患者。它在其他类型的后天性脑损伤中发生的频率较低。神经原性HO仅在少数帕金森病(PD)病例中有记录。它的治疗具有挑战性,可能需要缓解疼痛的方法。本文对一例复杂的帕金森病和脑卒中患者在康复过程中出现髋关节HO的过程和治疗方法进行了探讨。一名79岁的男性中风和帕金森病患者出现髋关节受限和疼痛。骨盆X线片发现双侧HO。他没有从运动、经皮神经电刺激或消炎痛中获益。放射治疗也被尝试用于治疗HO。之后,使用闭孔和股神经阻滞来缓解疼痛,疼痛减轻,坐姿平衡改善。HO是帕金森病和中风的一种罕见并发症,对康复过程有不利影响。由于治疗选择有限,可以考虑外周神经阻滞等姑息性疼痛管理方法。
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来源期刊
CiteScore
5.10
自引率
0.00%
发文量
132
审稿时长
2 months
期刊介绍: The International Journal of Neuroscience publishes original research articles, reviews, brief scientific reports, case studies, letters to the editor and book reviews concerned with problems of the nervous system and related clinical studies, epidemiology, neuropathology, medical and surgical treatment options and outcomes, neuropsychology and other topics related to the research and care of persons with neurologic disorders.  The focus of the journal is clinical and transitional research. Topics covered include but are not limited to: ALS, ataxia, autism, brain tumors, child neurology, demyelinating diseases, epilepsy, genetics, headache, lysosomal storage disease, mitochondrial dysfunction, movement disorders, multiple sclerosis, myopathy, neurodegenerative diseases, neuromuscular disorders, neuropharmacology, neuropsychiatry, neuropsychology, pain, sleep disorders, stroke, and other areas related to the neurosciences.
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