Fractional laser combined with 5-Aminolevulinic acid photodynamic therapy for the treatment of Cutaneous Rosai-Dorfman Disease: A case report.

Photodiagnosis and photodynamic therapy Pub Date : 2023-12-01 Epub Date: 2023-10-18 DOI:10.1016/j.pdpdt.2023.103852
Huan Wang, Chunyou Wang, Xin Wang, Lian Zhang, Min Zhang, Lan Ge, Yi You
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Abstract

Rosai-Dorfman disease(RDD) is a rare benign histiocytic proliferative disorder. Cutaneous Rosai-Dorfman disease(CRDD)is a rare variant of RDD with lesions localized to the skin. We report a case of patients with CRDD who was refractory to methotrexate, thalidomide, cyclosporine, glucocorticoid for local injection and external use, but resolved with fractional laser combined with 5-aminolevulinic acid photodynamic therapy (ALA-PDT). We believe that fractional laser technology combined with ALA-PDT for CRDD is a minimally invasive, effective and satisfactory treatment.

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部分激光联合5-氨基乙酰丙酸光动力疗法治疗皮肤Rosai-Dorfman病一例报告。
Rosai Dorfman病(RDD)是一种罕见的良性组织细胞增殖性疾病。皮肤Rosai Dorfman病(CRDD)是一种罕见的RDD变体,病变局限于皮肤。我们报告了一例CRDD患者,该患者对甲氨蝶呤、沙利度胺、环孢菌素、糖皮质激素局部注射和外用都有难治性,但通过部分激光联合5-氨基乙酰丙酸光动力疗法(ALA-PDT)解决。我们认为,部分激光技术结合ALA-PDT治疗CRDD是一种微创、有效和令人满意的治疗方法。
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