Current perspectives of sudden cardiac death management in hypertrophic cardiomyopathy.

IF 4.5 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Heart Failure Reviews Pub Date : 2024-03-01 Epub Date: 2023-10-22 DOI:10.1007/s10741-023-10355-w
Lutong Pu, Jialin Li, Weitang Qi, Jinquan Zhang, Hongyu Chen, Zihuan Tang, Yuchi Han, Jie Wang, Yucheng Chen
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Abstract

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder characterized by left ventricular hypertrophy. Sudden cardiac death (SCD) is a rare but the most catastrophic complication in patients with HCM. Implantable cardioverter-defibrillators (ICDs) are widely recognized as effective preventive measures for SCD. Individualized risk stratification and early intervention in HCM can significantly improve patient prognosis. In this study, we review the latest findings regarding pathogenesis, risk stratification, and prevention of SCD in HCM patients, highlighting the clinic practice of cardiovascular magnetic resonance imaging for SCD management.

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肥厚型心肌病心源性猝死管理的最新进展。
肥厚型心肌病(HCM)是一种以左心室肥大为特征的常染色体显性遗传疾病。心源性猝死(SCD)是HCM患者中一种罕见但最严重的并发症。植入式心律转复除颤器(ICD)被广泛认为是SCD的有效预防措施。HCM的个体化风险分层和早期干预可以显著改善患者预后。在这项研究中,我们回顾了HCM患者SCD的发病机制、风险分层和预防的最新发现,强调了心血管磁共振成像用于SCD治疗的临床实践。
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来源期刊
Heart Failure Reviews
Heart Failure Reviews 医学-心血管系统
CiteScore
10.40
自引率
2.20%
发文量
90
审稿时长
6-12 weeks
期刊介绍: Heart Failure Reviews is an international journal which develops links between basic scientists and clinical investigators, creating a unique, interdisciplinary dialogue focused on heart failure, its pathogenesis and treatment. The journal accordingly publishes papers in both basic and clinical research fields. Topics covered include clinical and surgical approaches to therapy, basic pharmacology, biochemistry, molecular biology, pathology, and electrophysiology. The reviews are comprehensive, expanding the reader''s knowledge base and awareness of current research and new findings in this rapidly growing field of cardiovascular medicine. All reviews are thoroughly peer-reviewed before publication.
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