Dermis fat graft compared to temporalis myofascial graft for interpositional arthroplasty in TMJ ankylosis. A systematic review and metanalysis

Ashutosh Kumar Singh , Anson Jose , Nikita Khanal , K.C. Krishna , Rajib Chaulagain , Ajoy Roychoudhury
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Abstract

This systematic review was performed to compare the dermis fat graft (DFG) to the conventional temporalis myofascial flap (TMF) used as Interpositional material in the management of temporomandibular joint ankylosis (TMJA). We searched PubMed, Embase, CENTRAL, clinical trial registries and google scholar. The outcomes of interest were Maximal Incisal Opening (MIO), Post-operative pain and reankylosis. Only four studies met the inclusion criteria. The studies had an overall high risk of bias. Nevertheless, the MIO was higher by 4.485 mm in DFG which was statistically significant (p < 0.01) but heterogenous (I2 = 92%). The risk difference of reankylosis was only 3% less in DFG compared to TMF, which was statistically not significant (p = 0.64). The post-operative pain was comparable between the two techniques, with only one study reporting a statistically significant reduction in pain in the DFG group. We found low-quality evidence of statistically significant higher MIO in DFG, but a very low risk difference in reankylosis between the two techniques. Further clinical trials with long-term follow-up are recommended as the total sample and outcome events are very low for a concrete conclusion.

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真皮脂肪移植术与颞肌筋膜移植术治疗颞下颌关节强直的比较。系统回顾和荟萃分析
本系统综述旨在比较真皮脂肪移植物(DFG)与传统颞肌筋膜瓣(TMF)在颞下颌关节强直(TMJA)治疗中的应用。我们搜索了PubMed、Embase、CENTRAL、临床试验注册中心和谷歌学者。感兴趣的结果是最大切口开放(MIO)、术后疼痛和再烷基化。只有四项研究符合纳入标准。这些研究总体上存在较高的偏倚风险。然而,DFG中的MIO高出4.485mm,这在统计学上是显著的(p<0.01),但不均匀(I2=92%)。与TMF相比,DFG的再烷基化风险差异仅低3%,这在统计学上并不显著(p=0.64)。两种技术的术后疼痛具有可比性,只有一项研究报告DFG组的疼痛在统计学上显著减轻。我们发现低质量的证据表明,DFG中的MIO在统计学上显著较高,但两种技术在再烷基化方面的风险差异非常低。建议进行进一步的长期随访临床试验,因为总样本和结果事件非常低,无法得出具体结论。
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