Treatment of an oral malignant lesion following mucosal insult; a case report

Zilefac Brian Ngokwe , Ntep Ntep David Bienvenue , Aminkeng Azicha Shannen , Nokam Kamdem Stephane , Bola Siafa Antoine , Sando Zacharie
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Abstract

Head and neck squamous cell carcinomas (HNSCCs) are aggressive cancers with high morbidity and low survival rates, as well as limited therapeutic options.

We present the case of a 54-year-old patient, person living with HIV/AIDS (PLWH) who presented with a history of an ulcerating lesion in her soft palate following self-inflicted mucosal insult which later revealed as an invasive squamous cell carcinoma with high grade dysplasia.

The patient underwent chemotherapy and demonstrated remarkable clinical recovery with complete remission of signs and symptoms.

We present a case in which early diagnosis and interdisciplinary collaboration were critical in ensuring a good prognosis for the patient, who is at the moment of writing, asymptomatic.

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口腔黏膜损伤后恶性病变的治疗病例报告
头颈部鳞状细胞癌是一种侵袭性癌症,发病率高,生存率低,治疗选择有限。我们报告了一例54岁的患者,艾滋病病毒/艾滋病患者(PLWH),她在自我造成粘膜损伤后,有软腭溃疡病变史,后来发现是一种侵袭性鳞状细胞癌伴高度发育不良。患者接受了化疗,表现出显著的临床康复,体征和症状完全缓解。我们提出了一个病例,在该病例中,早期诊断和跨学科合作对于确保患者的良好预后至关重要,在撰写本文时,患者没有症状。
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