A prospective observational 2D/3D/4D hysterosalpingo contrast sonography using mixture of lignocaine gel and normal saline as contrast in patients undergoing infertility investigations

Chegondi V. Narayanarao
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Abstract

Background and aim

Hysterosalpingo contrast sonography (HyCoSy) is a well-tolerated diagnostic tool to examine the uterus, ovaries, fallopian tubes, and pelvis. It has some advantages over other techniques, such as X-ray hysterosalpingography (HSG), laparoscopy, and dye intubation. This prospective study aimed to investigate the use of 2D/3D/4D HyCoSy, using lignocaine gel and normal saline as a contrast agent, to assess tubal patency and uterine abnormalities in infertile women.

Method

More than 5000 infertile cases were evaluated by HyCoSy 2D/3D/4D test using lignocaine gel as a contrast agent during the period of 2016–2022 at Shilpa Scanning Center, Andhra Pradesh. Among the subjects studied, a total of 850 cases were randomly selected to assess tubal patency. Of 850 patients, 54 had X-ray HSG reports that were reassessed using 2D/3D/4D HyCoSy. During the test, we also assess the intensity of the pain.

Results

Out of 850 infertile patients, 603 (70.94%) had primary infertility, and 247 (29.06%) had secondary infertility. The fallopian tubes were found to be patent in 702 (82.59%) of these patients, while 80 (9.41%) had unilateral occlusion and 68 (8%) had bilateral occlusion. Among the 54 patients with previous reports of X-ray HSG, three were misdiagnosed as bilateral obstruction and six as unilateral obstruction, and these misdiagnoses were confirmed by 2D/3D/4D HyCoSy using lignosal contrast and laparoscopic dye testing. During the HyCoSy procedure, 772 women (90.82%) reported mild pain that was less severe than menstrual pain.

Conclusions

The 2D/3D/4D-HyCoSy with lignosal gel as a contrast agent could be a promising tool for detecting fallopian tube patency and uterine abnormalities.

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采用利多卡因凝胶与生理盐水混合作对比剂对不孕症患者进行子宫输卵管造影2D/3D/4D前瞻性观察
背景和目的子宫输卵管造影(HyCoSy)是一种耐受性良好的诊断工具,用于检查子宫、卵巢、输卵管和骨盆。它比其他技术有一些优势,如X射线子宫输卵管造影(HSG)、腹腔镜和染料插管。本前瞻性研究旨在研究2D/3D/4D HyCoSy的使用,使用利多卡因凝胶和生理盐水作为对比剂,评估不孕妇女的输卵管通畅性和子宫异常。方法2016-2022年期间,在安得拉邦Shilpa扫描中心,使用利多卡因凝胶作为造影剂,通过HyCoSy 2D/3D/4D测试对5000多例不孕病例进行了评估。在所研究的受试者中,共有850例被随机选择来评估输卵管通畅性。在850名患者中,54名患者的X射线HSG报告使用2D/3D/4D HyCoSy进行了重新评估。在测试过程中,我们还评估了疼痛的强度。结果850例不孕患者中,原发性不孕603例(70.94%),继发性不孕247例(29.06%)。其中702例(82.59%)患者输卵管通畅,80例(9.41%)患者单侧输卵管闭塞,68例(8%)患者双侧输卵管闭塞。在54例既往有X射线HSG报告的患者中,3例被误诊为双侧梗阻,6例被诊断为单侧梗阻,这些误诊是通过2D/3D/4D HyCoSy使用木质素造影剂和腹腔镜染色测试证实的。在HyCoSy手术过程中,772名女性(90.82%)报告轻度疼痛,其严重程度低于月经疼痛。结论以木质素凝胶为造影剂的2D/3D/4D HyCoSy可作为检测输卵管通畅和子宫异常的一种很有前途的工具。
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