{"title":"MALT lymphoma of the palatal minor salivary Grand in patient with Sjögren's syndrome: A case report","authors":"Harusachi Kanazawa , Kohei Kawasaki , Isao Miyamoto , Atsusi Kasamatsu , Katsuhiro Uzawa , Masashi Fukuyama","doi":"10.1016/j.omsc.2023.100336","DOIUrl":null,"url":null,"abstract":"<div><p>We present a quite rare case of MALT lymphoma originating from the palatal minor salivary gland in a 37-year-old woman with Sjögren's syndrome (SS). She underwent an excision biopsy and definite diagnosis of MALT lymphoma was obtained on the basis of microscopic finding with lymphoepithelial lesion, immunohistochemistry positive for CD20 and negative for CD3, CD5, cycclinD1, and detection of immunoglobulin light chain restriction with kappa light-chain restricted monoclonality. MALT lymphoma is considered in the differential diagnosis of a painless, non-ulcerative palatal swelling. In this case, SS remained undiagnosed until after MALT lymphoma diagnosis. Patients with MALT lymphoma in the minor salivary glands need to be investigated for SS even if there is no clinical symptom of SS. Surgical excision can be recommended in case of limited stages resulting in good prognosis.</p></div>","PeriodicalId":38030,"journal":{"name":"Oral and Maxillofacial Surgery Cases","volume":"9 4","pages":"Article 100336"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral and Maxillofacial Surgery Cases","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214541923000457","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 0
Abstract
We present a quite rare case of MALT lymphoma originating from the palatal minor salivary gland in a 37-year-old woman with Sjögren's syndrome (SS). She underwent an excision biopsy and definite diagnosis of MALT lymphoma was obtained on the basis of microscopic finding with lymphoepithelial lesion, immunohistochemistry positive for CD20 and negative for CD3, CD5, cycclinD1, and detection of immunoglobulin light chain restriction with kappa light-chain restricted monoclonality. MALT lymphoma is considered in the differential diagnosis of a painless, non-ulcerative palatal swelling. In this case, SS remained undiagnosed until after MALT lymphoma diagnosis. Patients with MALT lymphoma in the minor salivary glands need to be investigated for SS even if there is no clinical symptom of SS. Surgical excision can be recommended in case of limited stages resulting in good prognosis.
期刊介绍：
Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports and case series only which must be original, educational, rare conditions or findings, or clinically interesting to an international audience of surgeons and clinicians. Case series can be prospective or retrospective and examine the outcomes of management or mechanisms in more than one patient. Case reports may include new or modified methodology and treatment, uncommon findings, and mechanisms. All case reports and case series will be peer reviewed for acceptance for publication in the Journal.
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