Peritonitis primaria por neumococo en un hospital pediátrico de Argentina

IF 2.1 4区 生物学 Q4 MICROBIOLOGY Revista Argentina de microbiologia Pub Date : 2023-07-01 Epub Date: 2023-03-17 DOI:10.1016/j.ram.2023.01.001
Mónica E. Martínez , Sandra L. Grenón , Jessica Benítez , Celia Labán , Marta E. Mollerach , Martha H. von Specht
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Abstract

Pneumococcal peritonitis represents a small subset of patients suffering from invasive pneumococcal disease (IPD). We describe 5 cases of primary peritonitis documented in the pediatric hospital over 15 years (2005-2020) of IPD surveillance. The patients, 3 girls and 2 boys with a mean age of 5 years, experienced peritoneal signs and symptoms; 3 of them suffered from nephrotic syndrome. Based on the local resistance profiles, all isolates were sensitive to beta-lactams, one strain showed resistance to cotrimoxazole and tetracycline while another strain, to cotrimoxazole only. Serotypes found in 4/5 strains (one was non-viable) were: 1, 19F, 15C and 23A. Children were treated with third-generation cephalosporins or ampicillin, gentamicin and metronidazole and all of them evolved favorably. Pneumococcal etiology should be included in the differential diagnosis of acute abdominal pain in children. Our study aims to contribute to the knowledge of this condition and to the local epidemiology of IPD.

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阿根廷一家儿科医院的原发性肺炎腹膜炎
肺炎球菌性腹膜炎是侵袭性肺炎球菌疾病(IPD)患者的一小部分。我们描述了儿科医院在IPD监测的15年(2005-2020)中记录的5例原发性腹膜炎病例。患者,3名女孩和2名男孩,平均年龄5岁,出现腹膜体征和症状;其中3例为肾病综合征。根据局部耐药性谱,所有分离株对β-内酰胺敏感,其中一株对复方新诺明和四环素表现出耐药性,而另一株仅对复方新诺明表现出耐药性。在4/5株(其中一株不活)中发现的血清类型为:1、19F、15C和23A。儿童接受了第三代头孢菌素或氨苄青霉素、庆大霉素和甲硝唑的治疗,所有这些药物都有良好的进化。肺炎球菌病因应纳入儿童急性腹痛的鉴别诊断。我们的研究旨在为了解这种情况和IPD的当地流行病学做出贡献。
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来源期刊
CiteScore
3.30
自引率
0.00%
发文量
46
审稿时长
>12 weeks
期刊介绍: La Revista Argentina de Microbiología es una publicación trimestral editada por la Asociación Argentina de Microbiología y destinada a la difusión de trabajos científicos en las distintas áreas de la Microbiología. La Asociación Argentina de Microbiología se reserva los derechos de propiedad y reproducción del material aceptado y publicado.
期刊最新文献
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