Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortality

IF 0.6 Q4 SURGERY Surgery in practice and science Pub Date : 2023-06-01 DOI:10.1016/j.sipas.2023.100163

Dr Alok Anshu , Dr Surjeet Dwivedi , Dr M Murali , Dr Harsha MP

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Abstract

Background

Necrotizing soft tissue infections (NSTI) and non-NSTI are frequently difficult to distinguish based on symptoms, signs, and investigations. High morbidity related to it can only be avoided by early detection and treatment.

Aim

This study examined demographic, clinicopathological, NSTI prognosis, and mortality factors.

Methodology

80 NSTI patients were retrospectively studied. Clinicopathological profile, surgical management, histological report, and LRINEC score were included. Mortality predictions were evaluated between survivors and non-survivors.

Results

73.8 percent of patients were male and the mean age was 55.4±9.6 years. Nonsurvivors averaged 11.88±0.72 LRINEC scores. Non-survivor CRP averaged 236.5±48.5 mg/l. Gp A Hemolytic Streptococci were most frequent (37.8 percent ). Diabetes was a significant mortality predictor. Total mortality was 20%.

Conclusion

NSTI remains a major killer. High mortality is linked to age, diabetes, higher blood creatinine, MODS, and delayed surgery.” and proceed accordingly.

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坏死性软组织感染在当今时代:临床病理特征和死亡率预测因素的分析

背景:坏死性软组织感染(NSTI)和非NSTI通常很难根据症状、体征和检查来区分。只有通过早期发现和治疗才能避免与之相关的高发病率。目的研究人口统计学、临床病理、NSTI预后和死亡率因素。方法对80例NSTI患者进行回顾性分析。包括临床病理、手术处理、组织学报告和LRINEC评分。结果73.8%的患者为男性，平均年龄为55.4±9.6岁。非幸存者平均LRINEC得分为11.88±0.72。非幸存者CRP平均值为236.5±48.5 mg/l。以Gp A溶血性链球菌最为常见(37.8%)。糖尿病是一个重要的死亡率预测因子。总死亡率为20%。结论nsti仍是主要杀手。高死亡率与年龄、糖尿病、高血肌酐、MODS和延迟手术有关。，然后继续进行。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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