Outcome of a 2-stage management of open tibia fracture in a low-income country lacking plastic surgeons: A retrospective cohort study

Loïc Fonkoue , Kennedy Olivier Muluem , Theophile Nana , Denis Kong , Olivier Ngongang , Marie Ange Ngo Yamben , Urich Tambekou , Jules Tagakou , Eone Daniel Handy
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Abstract

Background

Given the multiple constraints preventing optimal management of open tibia fracture (OTF) and lack of plastic surgeons in the entire country, we developed a two-stage approach. This study aimed to assess the outcome of this approach and identify factors influencing the outcome.

Methods

Consecutive series of 158 patients with OTF managed according to our two-stage protocol, with a minimum follow-up period of 12 months, from July 2015 to June 2021 ​at a tertiary care hospital in Yaoundé (Cameroon), were retrospectively reviewed. Patients were invited to return for a prospective ultimate radio-clinical evaluation. Main outcomes included bone union, functional status, severe complications and reoperation rate. Multivariate logistic regression was used to determine the independent predictors of severe complications.

Results

The mean follow-up period was 30.02 ​± ​17.05 months. Surgical site infection (SSI) was the main early complication, found in 44 (36.4%) cases. The main delayed complications was fracture-related infection in 36 (29.8%) cases. At final follow-up, only 64 (52.9%) patients had achieved bone union without any complication. The reoperation rate was 36.02%. Severe complications at final follow-up included nonunion in 13 (10.3%) patients, chronic osteomyelitis in 17 (14%) patients and amputation in 5 (4.1%) patients. In multivariable logistic regression, the only independents predictors of severe complications were severe OTF [OR ​= ​0.08, 95%CI: 0.02–0.30, P ​< ​0.001] and SSI [OR ​= ​4.53, 95%CI: 1.36–15.02, P ​< ​0.01].

Conclusion

Despite the progress observed with our 2-stage approach, nearly half of patients still develop complications. This study highlights the need for orthoplastic approach of OTF in developing countries.

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在一个缺乏整形外科医生的低收入国家,开放性胫骨骨折两期治疗的结果:一项回顾性队列研究
背景:考虑到阻碍开放性胫骨骨折(OTF)最佳治疗的多重限制因素以及整个国家缺乏整形外科医生,我们开发了一种两阶段的方法。本研究旨在评估该方法的结果,并确定影响结果的因素。方法回顾性分析2015年7月至2021年6月在喀麦隆雅温得(yaound)的一家三级保健医院,根据我们的两阶段方案管理的连续158例OTF患者,随访期至少为12个月。患者被邀请返回进行前瞻性最终放射-临床评估。主要观察骨愈合、功能状况、严重并发症及再手术率。采用多因素logistic回归确定严重并发症的独立预测因素。结果平均随访时间为30.02±17.05个月。手术部位感染(SSI)是主要的早期并发症,44例(36.4%)。延迟并发症主要为骨折相关感染36例(29.8%)。最后随访时,仅有64例(52.9%)患者骨愈合无并发症。再手术率为36.02%。最终随访时的严重并发症包括13例(10.3%)患者骨不连,17例(14%)患者患有慢性骨髓炎,5例(4.1%)患者截肢。在多变量logistic回归中,严重并发症的独立预测因子只有严重的OTF [OR = 0.08, 95%CI: 0.02-0.30, P <0.001)和SSI(或= 4.53,95%置信区间ci: 1.36 - -15.02, P & lt;0.01]。结论:尽管我们的两阶段方法取得了进展,但仍有近一半的患者出现并发症。本研究强调了发展中国家对OTF矫形方法的需求。
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