Advances and prospects of drug clinical research in colorectal cancer in 2022

Cancer Innovation Pub Date : 2023-03-05 DOI:10.1002/cai2.62
Dan Su, Chao Liu, Jie Cui, Jiebing Tang, Yuli Ruan, Yanqiao Zhang
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Abstract

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer death worldwide. Clinical research results have provided more treatment opportunities for CRC patients, showing that an optimal combination of existing drugs and new drugs is needed to mitigate the burden of this disease. In this review, we have summarized recent advances in drug clinical research for CRC in 2022, including chemotherapy, targeted therapy, and immunotherapy, to find opportunities for substantial improvements in drug discovery and clinical development methods.

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2022年癌症药物临床研究进展与展望
癌症是癌症中第三常见的癌症,也是全球癌症死亡的第二大原因。临床研究结果为CRC患者提供了更多的治疗机会,表明需要现有药物和新药的最佳组合来减轻这种疾病的负担。在这篇综述中,我们总结了2022年CRC药物临床研究的最新进展,包括化疗、靶向治疗和免疫疗法,以寻找在药物发现和临床开发方法方面取得实质性改进的机会。
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