Correlations behind macrotrabecular-massive and vessels encapsulating tumor cluster patterns in hepatocellular carcinoma

iRadiology Pub Date : 2023-03-27 DOI:10.1002/ird3.13
Yong-Wen Sun, Yu-Peng Chen, Shi-Ji Kan, Ya-Dong Liu, Zhi-bing Ruan, Bo Gao
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Abstract

Macrotrabecular-massive hepatocellular carcinoma (MTM-HCC) is a subtype of HCC with a very poor prognosis and exhibits biological behaviors and clinical presentations that distinguish it from conventional HCC. Vessels encapsulating tumor clusters (VETC) is a unique pattern of vascular growth that is more common in patients with MTM-HCC. This unique interaction between the angiogenic system and tumor cells is of general interest. Early diagnosis and appropriate treatment of HCC with MTM and VETC patterns help prevent early recurrence and improve prognosis. This review summarizes the existing findings for HCC with MTM and VETC patterns.

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肝细胞癌大骨小梁块和血管包裹肿瘤簇模式背后的相关性
大骨小梁块状肝细胞癌(MTM-HCC)是一种预后极差的HCC亚型,其生物学行为和临床表现与传统HCC不同。包裹肿瘤簇的血管(VETC)是一种独特的血管生长模式,在MTM-HCC患者中更常见。血管生成系统和肿瘤细胞之间的这种独特的相互作用是普遍感兴趣的。MTM和VETC模式对HCC的早期诊断和适当治疗有助于预防早期复发并改善预后。这篇综述总结了具有MTM和VETC模式的HCC的现有研究结果。
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