Progress in research on ultrasound radiomics for predicting the prognosis of breast cancer

Cancer Innovation Pub Date : 2023-07-11 DOI:10.1002/cai2.85
Xuantong Gong, Xuefeng Liu, Xiaozheng Xie, Yong Wang
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Abstract

Breast cancer is the most common malignant tumor and the leading cause of cancer-related deaths in women worldwide. Effective means of predicting the prognosis of breast cancer are very helpful in guiding treatment and improving patients' survival. Features extracted by radiomics reflect the genetic and molecular characteristics of a tumor and are related to its biological behavior and the patient's prognosis. Thus, radiomics provides a new approach to noninvasive assessment of breast cancer prognosis. Ultrasound is one of the commonest clinical means of examining breast cancer. In recent years, some results of research into ultrasound radiomics for diagnosing breast cancer, predicting lymph node status, treatment response, recurrence and survival times, and other aspects, have been published. In this article, we review the current research status and technical challenges of ultrasound radiomics for predicting breast cancer prognosis. We aim to provide a reference for radiomics researchers, promote the development of ultrasound radiomics, and advance its clinical application.

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超声放射组学预测癌症预后的研究进展
癌症是最常见的恶性肿瘤,也是全球女性癌症相关死亡的主要原因。预测癌症预后的有效手段对指导治疗和提高患者生存率有重要意义。放射组学提取的特征反映了肿瘤的遗传和分子特征,并与其生物学行为和患者预后有关。因此,放射组学为乳腺癌症预后的无创评估提供了一种新的方法。超声检查是癌症最常见的临床检查手段之一。近年来,超声放射组学在诊断癌症、预测淋巴结状态、治疗反应、复发和存活时间等方面的一些研究成果已经发表。本文综述了超声放射组学在预测癌症预后方面的研究现状和技术挑战。旨在为放射组学研究人员提供参考,促进超声放射组学的发展,促进其临床应用。
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