Semi-Automatic Assessment of Vocalization Quality for Children With and Without Angelman Syndrome.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-11-01 DOI:10.1352/1944-7558-128.6.425
Lisa R Hamrick, Amanda Seidl, Bridgette L Kelleher
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Abstract

Automated methods for processing of daylong audio recordings are efficient and may be an effective way of assessing developmental stage for typically developing children; however, their utility for children with developmental disabilities may be limited by constraints of algorithms and the scope of variables produced. Here, we present a novel utterance-level processing (ULP) system that 1) extracts utterances from daylong recordings, 2) verifies automated speaker tags using human annotation, and 3) provides vocal maturity metrics unavailable through automated systems. Study 1 examines the reliability and validity of this system in low-risk controls (LRC); Study 2 extends the ULP to children with Angelman syndrome (AS). Results showed that ULP annotations demonstrated high coder agreement across groups. Further, ULP metrics aligned with language assessments for LRC but not AS, perhaps reflecting limitations of language assessments in AS. We argue that ULP increases accuracy, efficiency, and accessibility of detailed vocal analysis for syndromic populations.

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有和无天使人综合症儿童发声质量的半自动评估。
处理全天录音的自动化方法是有效的,并且可能是评估典型发育儿童发育阶段的有效方法;然而,它们对发育障碍儿童的效用可能受到算法的限制和产生的变量的范围的限制。在这里,我们提出了一种新的话语级处理(ULP)系统,该系统1)从一整天的录音中提取话语,2)使用人工注释验证自动说话人标签,3)提供通过自动系统无法获得的语音成熟度度量。研究1检验了该系统在低风险控制(LRC)中的可靠性和有效性;研究2将ULP扩展到患有Angelman综合征(AS)的儿童。结果显示,ULP注释显示出跨组的高编码一致性。此外,ULP指标与LRC的语言评估一致,但与AS不一致,这可能反映了AS中语言评估的局限性。我们认为,ULP提高了综合征人群详细语音分析的准确性、效率和可及性。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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