[Treatment of Ampullary Adenocarcinoma].

Dong Woo Shin
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Abstract

The ampulla of Vater is a small projection formed by the confluence of the main pancreatic duct and common bile duct in the second part of the duodenum. Primary ampullary adenocarcinoma is a rare malignancy, accounting for only 0.2% of gastrointestinal cancers and approximately 7% of all periampullary cancers. Jaundice from a biliary obstruction is the most common symptom of ampullary adenocarcinoma. In the early stages, radical pancreatoduodenectomy is the standard surgical approach. On the other hand, no randomized controlled trial has provided evidence to guide physicians on the choice of adjuvant/palliative chemotherapy because of the rarity of the disease and the paucity of related research. This paper reports the biology, histology, current therapeutic strategies, and potential future therapies of ampullary adenocarcinoma.

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壶腹腺癌的治疗。
沃特壶腹是由十二指肠第二部分的主胰管和总胆管汇合形成的一个小突起。原发性壶腹腺癌是一种罕见的恶性肿瘤,仅占胃肠道癌的0.2%,约占所有壶腹周围癌的7%。胆道梗阻引起的黄疸是壶腹腺癌最常见的症状。在早期阶段,根治性胰十二指肠切除术是标准的手术方法。另一方面,由于这种疾病的罕见性和相关研究的匮乏,没有随机对照试验提供证据来指导医生选择辅助/姑息化疗。本文报道壶腹腺癌的生物学、组织学、目前的治疗策略以及未来潜在的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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