Analysis of Prosthetic Replacement of the Ocular Surface Ecosystem Anterior Surface Condition Using Noninvasive Keratograph Break-Up Time.

IF 2 4区医学 Q2 OPHTHALMOLOGY Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-01-01 Epub Date: 2023-10-26 DOI:10.1097/ICL.0000000000001050

Kayla Nodecker, Sankirth Madabhushi, Daniel Brocks

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Abstract

Objectives: Noninvasive keratograph break-up time (NIKBUT) was developed as an alternative to fluorescein-based measurements of tear break-up time and may have utility not only for the objective evaluation of tear film stability on the corneal surface but also on the surface of scleral and contacts lenses. We report on two cases that highlight the potential use of NIKBUT to provide objective prelens tear film stability data to evaluate the anterior surface of a customized ocular surface prosthetic devices (PD; PROSE, BostonSight, Needham, MA).

Methods: Case report and literature review.

Results: Case 1 demonstrates improvement in prelens tear film stability with NIKBUT increasing from 4.59 to 11.47 sec after the addition of a polyethylene glycol-based polymer coating to the PD surface. In case 2, when a NIKBUT value could not be obtained, keratograph infrared images were used to evaluate improved anterior lens surface wetting.

Conclusion: Noninvasive keratograph break-up time may provide an objective modality to evaluate prelens tear film stability and PD wettability. Such measurements may allow for a better understanding of visual degradation related to PD lens condition and the appropriate timing of lens recoating, reconditioning, and replacement.

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利用无创角膜磨镶仪破裂时间分析人工角膜表面生态系统前表面状况。

目的：非侵入性角膜曲率仪破裂时间（NIKBUT）是一种基于荧光素的泪液破裂时间测量方法的替代方法，不仅可用于客观评估角膜表面泪膜的稳定性，还可用于巩膜和隐形眼镜表面的泪膜稳定性。我们报告了两个病例，强调了NIKBUT的潜在用途，以提供客观的晶状体前泪膜稳定性数据，评估定制眼表面假体装置（PD；PROSE，BostonSight，Needham，MA）的前表面。方法：病例报告和文献综述。结果：案例1表明，在PD表面添加聚乙二醇基聚合物涂层后，NIKBUT从4.59秒增加到11.47秒，晶状体前泪膜稳定性得到改善。在情况2中，当不能获得NIKBUT值时，使用角膜曲率仪红外图像来评估改善的晶状体前表面润湿性。结论：非侵入性角膜曲率仪破裂时间可作为评价晶状体前泪膜稳定性和局部浸润性的客观方法。这样的测量可以更好地了解与PD透镜状况相关的视觉退化，以及透镜重新涂覆、修复和更换的适当时机。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eye & Contact Lens-Science and Clinical Practice OPHTHALMOLOGY-

CiteScore

4.50

自引率

4.30%

发文量

150

审稿时长

6-12 weeks

期刊介绍： Eye & Contact Lens: Science and Clinical Practice is the official journal of the Contact Lens Association of Ophthalmologists (CLAO), an international educational association for anterior segment research and clinical practice of interest to ophthalmologists, optometrists, and other vision care providers and researchers. Focusing especially on contact lenses, it also covers dry eye disease, MGD, infections, toxicity of drops and contact lens care solutions, topography, cornea surgery and post-operative care, optics, refractive surgery and corneal stability (eg, UV cross-linking). Peer-reviewed and published six times annually, it is a highly respected scientific journal in its field.