Impacto pronóstico de los factores de riesgo cardiovascular en pacientes ingresados por síndrome coronario agudo

IF 1.2 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Hipertension y Riesgo Vascular Pub Date : 2023-07-01 DOI:10.1016/j.hipert.2022.09.004
J.E. Puche , M. Iturregui-Guevara , R. Vázquez
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Abstract

Introduction and objectives

Cardiovascular prevention measures place the emphasis on controlling cardiovascular risk factors (CVRF). However, the most recent studies provide disappointing data, the impact of which remains to be determined. The objective of this study was to analyse the impact that the different CVRFs, and their degree of control, have on the prognosis of patients after acute coronary syndrome.

Patients and methods

Epidemiological, pharmacological, and CVRF control data were collected from 1,689 consecutive patients admitted from 2018 to 2020 for acute coronary syndrome to a tertiary hospital. Finally, the rate of major adverse cardiovascular events was calculated.

Results

The patients admitted for acute coronary syndrome were predominantly men, with body mass index > 25 Kg/m2, smokers (or former smokers) and with poor CVRF control (50% for hypertension and diabetes and 35% for dyslipidaemia), especially those patients with a personal history of ischaemic heart disease. An underutilisation of useful drugs for CVRF control was found. A directly proportional relationship was observed between the number of CVRFs (or their poor control) and the incidence of major adverse cardiovascular events at 2 years, hypertension being the factor with the greatest cardiovascular impact. The SARS-CoV-2 lockdown worsened the degree of CVRF control and cardiovascular prognosis.

Conclusion

There is still room for improvement in the control of CVRF, which would translate into a prognostic benefit for patients with ischaemic heart disease. The implementation of cardiovascular prevention campaigns seems essential.

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心血管危险因素对急性冠状动脉综合征患者预后的影响
引言与目的心血管预防措施强调控制心血管危险因素(CVRF)。然而,最近的研究提供了令人失望的数据,其影响仍有待确定。本研究的目的是分析不同CVRF及其控制程度对急性冠状动脉综合征患者预后的影响。患者和方法从2018年至2020年因急性冠状动脉综合征连续入住三级医院的1689名患者中收集流行病学、药理学和CVRF对照数据。最后,计算主要心血管不良事件的发生率。结果急性冠状动脉综合征患者以男性为主,体重指数>;25公斤/平方米,吸烟者(或以前的吸烟者)和CVRF控制不佳(50%用于高血压和糖尿病,35%用于血脂异常),尤其是那些有缺血性心脏病个人病史的患者。发现对CVRF控制有用的药物利用不足。观察到CVRF的数量(或其不良控制)与2年时主要心血管不良事件的发生率之间存在直接的比例关系,高血压是心血管影响最大的因素。严重急性呼吸系统综合征冠状病毒2型封锁使CVRF控制程度和心血管预后恶化。结论CVRF的控制仍有改进的空间,这将转化为缺血性心脏病患者的预后益处。开展心血管预防运动似乎至关重要。
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来源期刊
Hipertension y Riesgo Vascular
Hipertension y Riesgo Vascular Medicine-Internal Medicine
CiteScore
1.70
自引率
16.70%
发文量
38
审稿时长
39 days
期刊介绍: La mejor publicación para mantenerse al día en los avances de la lucha contra esta patología. Incluye artículos de Investigación, Originales, Revisiones, Casos clínicos, Aplicación práctica y Resúmenes comentados a la bibliografía internacional. Además, es la Publicación Oficial de la Sociedad española de Hipertensión-Liga Española para la Lucha contra la Hipertensión Arterial.
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