Headache and papilledema: A case of neurosarcoidosis with cerebrovascular involvement

Karlo Toljan , Albert Aboseif , J. Daniel Bireley , Brandon Moss
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Abstract

Background

Cerebrovascular involvement of neurosarcoidosis is a rare albeit increasingly recognized disorder requiring a multidisciplinary approach to diagnosis and management.

Case description

We present a case of systemic sarcoidosis with neurological involvement of brain parenchyma and intracranial vasculature, and discuss a step-wise approach to the diagnostic evaluation.

Conclusion

An inflammatory vasculitis should be considered in a patient with confirmed or highly suspected sarcoidosis with ischemic stroke. MR angiography with vessel-wall imaging should be pursued early in the evaluation to support this diagnosis. Cerebrovascular complications of sarcoidosis are often responsive to sarcoid-related immunotherapies.

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头痛和视乳头水肿:一例脑血管受累的神经肉瘤
背景神经肉瘤的脑血管受累是一种罕见的疾病,尽管人们越来越认识到这种疾病需要多学科的诊断和治疗方法。病例描述我们报告了一例系统性结节病,伴有脑实质和颅内血管系统的神经系统受累,并讨论了诊断评估的逐步方法。结论确诊或高度怀疑结节病伴缺血性脑卒中的患者应考虑炎症性血管炎。应在评估早期进行血管壁成像的MR血管造影术,以支持这一诊断。结节病的脑血管并发症通常对结节病相关的免疫疗法有反应。
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