Karlo Toljan , Albert Aboseif , J. Daniel Bireley , Brandon Moss
{"title":"Headache and papilledema: A case of neurosarcoidosis with cerebrovascular involvement","authors":"Karlo Toljan , Albert Aboseif , J. Daniel Bireley , Brandon Moss","doi":"10.1016/j.nerep.2023.100165","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Cerebrovascular involvement of neurosarcoidosis is a rare albeit increasingly recognized disorder requiring a multidisciplinary approach to diagnosis and management.</p></div><div><h3>Case description</h3><p>We present a case of systemic sarcoidosis with neurological involvement of brain parenchyma and intracranial vasculature, and discuss a step-wise approach to the diagnostic evaluation.</p></div><div><h3>Conclusion</h3><p>An inflammatory vasculitis should be considered in a patient with confirmed or highly suspected sarcoidosis with ischemic stroke. MR angiography with vessel-wall imaging should be pursued early in the evaluation to support this diagnosis. Cerebrovascular complications of sarcoidosis are often responsive to sarcoid-related immunotherapies.</p></div>","PeriodicalId":100950,"journal":{"name":"Neuroimmunology Reports","volume":"3 ","pages":"Article 100165"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroimmunology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667257X23000037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Cerebrovascular involvement of neurosarcoidosis is a rare albeit increasingly recognized disorder requiring a multidisciplinary approach to diagnosis and management.
Case description
We present a case of systemic sarcoidosis with neurological involvement of brain parenchyma and intracranial vasculature, and discuss a step-wise approach to the diagnostic evaluation.
Conclusion
An inflammatory vasculitis should be considered in a patient with confirmed or highly suspected sarcoidosis with ischemic stroke. MR angiography with vessel-wall imaging should be pursued early in the evaluation to support this diagnosis. Cerebrovascular complications of sarcoidosis are often responsive to sarcoid-related immunotherapies.