Management of Baló Concentric Sclerosis with rituximab: A case study with long-term follow-up

Abstract

Background

: Baló concentric sclerosis (BCS) is a rare demyelinating disorder that overlaps with other demyelinating diseases. BCS usually present in the context of multiple sclerosis (MS) or preceding typical MS. It rarely presents as an isolated lesion, . IV methyl prednisolone (IVMP) is the mainstay in the treatment with various outcomes. Maintenance therapy is still not clearly defined.

Case presentation/case report: We present a case of isolated BCS that responded clinically and radiologically to long-term rituximab therapy.

Conclusion

: A definite guideline for treating patient with BCS either with MS or as isolated entity is still controversial. Our case reflects a remarkable response to rituximab in achieving clinical and radiological long-term remission.