Separation techniques for denaturation and degradation products of collagen and other fibrous proteins

Abstract

Chromatographic and electrophoretic techniques for the separation of denaturation and degradation products of collagen and other fibrous proteins are reviewed. Further progress in these techniques is to be expected, especially for myosin and keratin breakdown products, where the molecular interpretation of results is still missing. No such difficulties exist in the case of collagen, where the relation between fractions and spots which appear during chromatographic separations and their place in the collagen molecule has already been elucidated.