Isquemia crítica dos membros superiores – Manifestação inicial de arterite de células gigantes – Caso clínico

Rodolfo Abreu , João Monteiro e Castro , Hugo Rodrigues , Leonor Vasconcelos , Gonçalo Rodrigues , Anita Quintas , Rita Ferreira , Nelson Camacho , Maria Emília Ferreira , João Albuquerque e Castro , Luís Mota Capitão
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Abstract

Introduction

Giant Cell Arteritis (GCA) is a systemic inflammatory vasculitis of unknown etiology that occurs in older persons and can result in a wide variety of clinical presentations. The disease most commonly affects the extracranial branches of the carotid artery but has also been shown to involve, in 10 to 15%, the upper extremity arteries, mostly the subclavian, axillary and proximal brachial arteries.

Clinical Case

A 80 year‐old woman with a prior history of hypertension and cerebrovascular disease presented with ischemic rest pain of both upper limbs, with evidence of distal digital cyanosis. Complaints began two months earlier and progressively worsened. Workup CT‐scan showed complete occlusion of both axillary and proximal branchial arteries and thickening of the wall of both subclavian arteries, aorta and common femoral arteries suggesting vasculitis.

Corticosteroid therapy was promptly commenced. No significant improvement was present after 5 days of treatment, so the patient underwent bilateral carotid‐brachial bypass. After surgery there was complete resolution of the complaints and radial pulse was present bilaterally. After 6 months, the patient remained asymptomatic and bypasses were permeable.

Conclusion

This paper aims to present the case of a patient with the inaugural diagnosis of GCA who presented with bilateral and simultaneous critical ischemia. This condition required the realization of a rare revascularization procedure.

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上肢严重缺血-巨细胞动脉炎的初始表现-临床病例
巨细胞动脉炎(GCA)是一种病因不明的全身性炎症性血管炎,常见于老年人,可导致多种临床表现。该疾病最常影响颈动脉颅外分支,但也显示有10%至15%的人累及上肢动脉,主要是锁骨下动脉、腋窝动脉和臂近端动脉。临床病例:一名80岁女性,既往有高血压和脑血管疾病病史,表现为双上肢缺血性静息性疼痛,并伴有远端指紫。投诉开始于两个月前,并逐渐恶化。后续CT扫描显示腋窝和近端鳃裂动脉完全闭塞,锁骨下动脉、主动脉和股总动脉壁增厚,提示血管炎。立即开始皮质类固醇治疗。治疗5天后没有明显改善,因此患者接受了双侧颈动脉-肱动脉搭桥术。手术后症状完全消失,双侧桡动脉脉搏出现。6个月后,患者无症状,旁路通畅。结论本文报告了一例首次诊断为GCA的患者,其表现为双侧和同时严重缺血。这种情况需要实现一个罕见的血运重建程序。
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