A Comparison of Patient and Clinician Assessments of Functional Ability in Predicting Number of Hospitalizations for Older Patients with Left Ventricular Dysfunction

Donald E. Stull PhD , Karl Kosloski PhD , Kyle Kercher PhD
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Abstract

Objective

To compare the relative ability of patient self-assessments and clinician assessments of functional limitations for predicting hospitalizations for older adults with left ventricular dysfunction.

Study Design

Latent growth model analyses used secondary data from a clinical drug study, the Studies of Left Ventricular Dysfunction. Self-report and clinician-report data of patients' functional limitations were collected at baseline, and 6 weeks, 12 months, and 24 months postbaseline to assess the effects of an angiotensin-converting enzyme inhibitor versus placebo. Latent growth model analyses were used to assess the relative effect of baseline ratings and changes in these 2 ratings of patient functional limitations over the initial 2 years of the study (ie, the drug study component) as potential predictors of the number of hospitalizations occurring over 3 subsequent years.

Results

Data from 1099 patients aged 65+ years were analyzed. Both baseline patient assessments and changes in patient assessments of functional limitations were significant predictors of the number of subsequent hospitalizations (β = 0.119 and 0.273, respectively). This was not the case for clinician assessments. Moreover, baseline patient and clinician assessments of the patient's functional limitations were correlated at 0.42, indicating only a modest relationship between the 2 assessments.

Conclusions

These results demonstrate the greater utility of patient self-report measures for predicting hospitalizations. Incorporating patient-reported outcomes into clinical practice will expand understanding of the effect of diseases. Assessing changes in patient reports yields important insights into those patients more likely to have multiple admissions for heart failure.

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老年左心室功能障碍患者功能能力预测住院次数的比较
目的比较患者自我评估和临床医师功能限制评估在预测老年左心室功能障碍住院治疗中的相对能力。研究设计:潜在生长模型分析使用了一项临床药物研究——左心室功能障碍研究的二次数据。在基线、基线后6周、12个月和24个月收集患者功能限制的自我报告和临床报告数据,以评估血管紧张素转换酶抑制剂与安慰剂的效果。使用潜在增长模型分析来评估基线评分的相对影响,以及这两个评分在研究最初2年(即药物研究部分)中患者功能限制的变化,作为随后3年住院次数的潜在预测因子。结果对1099例65岁以上患者资料进行分析。基线患者评估和患者功能限制评估的变化都是后续住院次数的重要预测因子(β分别= 0.119和0.273)。这不是临床医生评估的情况。此外,基线患者和临床医生对患者功能限制的评估相关性为0.42,表明两种评估之间只有适度的关系。结论:这些结果表明,患者自我报告措施在预测住院治疗方面具有更大的效用。将患者报告的结果纳入临床实践将扩大对疾病影响的理解。评估患者报告的变化对那些更有可能因心力衰竭多次入院的患者有重要的见解。
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