Teoría de conjuntos aplicada al recuento de linfocitos y leucocitos: predicción de linfocitos T CD4 de pacientes con virus de la inmunodeficiencia humana/sida

Javier Rodríguez , Signed Prieto , Catalina Correa , María Fernanda Forero , Carlos Pérez , Yolanda Soracipa , Jessica Mora , Nichole Rojas , Diana Pineda , Fredy López
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引用次数: 12

Abstract

Based on set theory a predictive method of LT-CD4 count was developed based on the number of white blood cells and total lymphocytes. The method was applied to 500 samples, in order to confirm the method's predictive capacity. The data triplets of WBC/ml3, lymphocytes/ml3 and CD4/μl for each patient were organized in descending order according to the number of white blood cells and separated in groups of 1.000. Triplets were organized in sets A, B, C and D, and then AUC, BUD, and their intersections were established. Finally, the elements of each group were calculated and their corresponding percentage for each group of WBC was determined.

As a result it was found that five of the nine groups of WBC showed an assertive percentage of 80.39% or above, and percentages of 92.54% and 100% were obtained for groups of values below 4.000/ml3 and 3.000/ml3, respectively. Results confirm that the method can be effectively applied in a clinical setting regardless of statistical measurements, and will reduce human and economic resources.

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集合理论在淋巴细胞和白细胞计数中的应用:人类免疫缺陷病毒/艾滋病患者CD4 T淋巴细胞的预测
基于集合理论,提出了一种基于白细胞和淋巴细胞总数的LT-CD4计数预测方法。将该方法应用于500个样本,以验证该方法的预测能力。将每例患者的WBC/ml3、淋巴细胞/ml3和CD4/μl数据三联体按白细胞数降序排列,每1000个为一组。将三联体组织在A、B、C、D集合中,建立AUC、BUD及其交点。最后计算各组元素,并确定各组白细胞所占的百分比。结果发现,9组WBC中有5组的自信率在80.39%以上,低于4.000/ml3和3.000/ml3组的自信率分别为92.54%和100%。结果证实,该方法可以有效地应用于临床设置,无论统计测量,并将减少人力和经济资源。
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