A live vaccine is safe and efficient to protect poultry against histomonosis

Michael Hess, Dieter Liebhart
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Abstract

The protozoan parasite Histomonas meleagridis is the aetiological agent of histomonosis, a highly fatal disease in turkeys with less mortality in chickens. Following the ban of licensed drugs to be used for prophylactic and therapeutic treatment the number of outbreaks increased in recent years, without any suitable and legal option to combat the disease. In various cases the whole flock had to be killed in order to reduce suffering of animals highlighting the importance histomonosis has gained also in the light of animal welfare. Considering the difficulties for licensing new drugs to be used in food producing animals, vaccination would be a new option to combat the disease. In the following presentation the efforts are consecutively presented leading to a safe and efficient vaccine, without any side effects on health and performance of birds. This vaccine could be the basis to prevent suffering and loss of animals due to a non-treatable disease.

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活疫苗对保护家禽免受组织病的侵害是安全有效的
原生动物寄生虫组织胞菌是组织胞菌病的病原,组织胞菌病是火鸡中一种高度致命的疾病,而鸡的死亡率较低。在禁止许可用于预防和治疗的药物之后,近年来爆发的次数有所增加,没有任何适当和合法的办法来防治这种疾病。在许多情况下,为了减少动物的痛苦,整个羊群都必须被杀死,这突出了组织病在动物福利方面的重要性。考虑到许可用于生产食品的动物的新药的困难,疫苗接种将是对抗这种疾病的一个新选择。在下面的介绍中,将连续介绍为研制安全有效的疫苗所做的努力,这种疫苗不会对禽类的健康和生产性能产生任何副作用。这种疫苗可以成为防止动物因无法治愈的疾病而遭受痛苦和损失的基础。
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