Su-Hwan Kim , Su-Yeon Lee , Yong-Moo Lee , Young-Kyoo Lee
{"title":"MicroRNAs as biomarkers for dental diseases","authors":"Su-Hwan Kim , Su-Yeon Lee , Yong-Moo Lee , Young-Kyoo Lee","doi":"10.1016/j.sdj.2015.09.001","DOIUrl":null,"url":null,"abstract":"<div><p>MicroRNAs (miRNAs) are short, noncoding RNAs that act as key regulators of diverse biological processes by mediating translational repression or mRNA degradation of target genes. Recent studies discovered miRNAs in saliva, and these miRNAs are promising candidates for use as biomarkers of dental diseases. In this review, the results of miRNA studies in the dental field are presented, and a brief overview of the current progress, limitations, and perspectives regarding miRNA biomarkers for dental diseases is given.</p></div>","PeriodicalId":35891,"journal":{"name":"Singapore Dental Journal","volume":"36 ","pages":"Pages 18-22"},"PeriodicalIF":0.0000,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.sdj.2015.09.001","citationCount":"17","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Singapore Dental Journal","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0377529115300109","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 17
Abstract
MicroRNAs (miRNAs) are short, noncoding RNAs that act as key regulators of diverse biological processes by mediating translational repression or mRNA degradation of target genes. Recent studies discovered miRNAs in saliva, and these miRNAs are promising candidates for use as biomarkers of dental diseases. In this review, the results of miRNA studies in the dental field are presented, and a brief overview of the current progress, limitations, and perspectives regarding miRNA biomarkers for dental diseases is given.
期刊介绍:
The scope of the journal covers all fields related to the presentday practice of dentistry, and includes Restorative Dentistry (Operative Dentistry, Dental Materials, Prosthodontics and Endodontics), Preventive Dentistry (Periodontics, Orthodontics, Paediatric Dentistry, Public Health and Health Services), Oral Medicine, Oral Surgery and Oral Pathology. Articles pertaining to dental education and the social, political and economic aspects of dental practice are also welcomed.