Light microscopic study on the tumor cell-associated antigens in patients with breast cancer by immunoperoxidase technique

I.K. Yantchev
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Abstract

Tumors from patients with breast cancer were examined by light microscopy using immunoperoxidase techniques. The positive immunoperoxidase reaction was observed in 12 of 19 tumors treated with autologous serum. The percentage of the labeled tumor cells was from 10–15 to 60–70. It was established that tumor cell-associated antigen(s) was located mainly on both, the plasma and the nuclear membrane. More rarely it could be seen on the chromatin.

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免疫过氧化物酶技术对乳腺癌患者肿瘤细胞相关抗原的光镜研究
使用免疫过氧化物酶技术光镜检查乳腺癌患者的肿瘤。自体血清治疗19例肿瘤,免疫过氧化物酶反应阳性12例。标记的肿瘤细胞百分比从10 - 15%到60 - 70%不等。结果表明,肿瘤细胞相关抗原主要位于血浆和核膜上。在染色质上更少见。
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