{"title":"Antiandrogen therapy in prostate cancer","authors":"Russell Z. Szmulewitz, Edwin M. Posadas","doi":"10.1016/j.uct.2007.10.003","DOIUrl":null,"url":null,"abstract":"<div><p>Antiandrogens are an important class of therapeutic agents for treatment of prostate cancer. While traditionally used as a second-line hormonal therapy following androgen deprivation treatment, they have been studied in a number of other settings. Antiandrogens continue to be a class of highly selective agents with relatively little toxicity compared to non-hormonal therapies for advanced disease. Compounds in development that target androgen receptor activation hold great promise for men with prostate cancer.</p></div>","PeriodicalId":87487,"journal":{"name":"Update on cancer therapeutics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.uct.2007.10.003","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Update on cancer therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1872115X07000485","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Antiandrogens are an important class of therapeutic agents for treatment of prostate cancer. While traditionally used as a second-line hormonal therapy following androgen deprivation treatment, they have been studied in a number of other settings. Antiandrogens continue to be a class of highly selective agents with relatively little toxicity compared to non-hormonal therapies for advanced disease. Compounds in development that target androgen receptor activation hold great promise for men with prostate cancer.
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