Enfermedad de Castleman: dos variantes, dos pacientes

Q4 Medicine Revista de Patologia Respiratoria Pub Date : 2011-10-01 DOI:10.1016/S1576-9895(11)70126-6

K. de Aguiar Quevedo , C. Jordá Aragón , N. Mancheño Franch , G. Sales Badía , V. Calvo Medina , A. García Zarza , J. Pastor Guillén

{"title":"Enfermedad de Castleman: dos variantes, dos pacientes","authors":"K. de Aguiar Quevedo , C. Jordá Aragón , N. Mancheño Franch , G. Sales Badía , V. Calvo Medina , A. García Zarza , J. Pastor Guillén","doi":"10.1016/S1576-9895(11)70126-6","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Castleman's disease (CD) is an uncommon lymphoproliferative disorder most frequently localized in the mediastinum and abdomen.</p><p>Two cases of CD with mediastinal localization in our service are described. The first case was found in a 33-year old woman with the plasma cell variant of CD associated to Hodgkin's disease and the second case was found in a 32 year old woman with hyalinevascular type CD.</p></div><div><h3>Discussion</h3><p>CD, of unknown etiology, is clinically distinguished with two forms, multicentric that affects more than one organ and occurs with general symptoms and can be accompanied by other involvements such as lymphoma. The second one is the localized one, which is more frequent and evolves asymptomatically or with compressive symptoms due to mass effect. In these cases presented, the difference in the clinical presentation of this condition in its two variants can be seen.</p></div><div><h3>Conclusions</h3><p>CD is an uncommon lymphoproliferative disease whose treatment is tumor resection and whose prognosis is good.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"14 4","pages":"Pages 138-142"},"PeriodicalIF":0.0000,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(11)70126-6","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de Patologia Respiratoria","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1576989511701266","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 5

Abstract

Introduction

Castleman's disease (CD) is an uncommon lymphoproliferative disorder most frequently localized in the mediastinum and abdomen.

Two cases of CD with mediastinal localization in our service are described. The first case was found in a 33-year old woman with the plasma cell variant of CD associated to Hodgkin's disease and the second case was found in a 32 year old woman with hyalinevascular type CD.

Discussion

CD, of unknown etiology, is clinically distinguished with two forms, multicentric that affects more than one organ and occurs with general symptoms and can be accompanied by other involvements such as lymphoma. The second one is the localized one, which is more frequent and evolves asymptomatically or with compressive symptoms due to mass effect. In these cases presented, the difference in the clinical presentation of this condition in its two variants can be seen.

Conclusions

CD is an uncommon lymphoproliferative disease whose treatment is tumor resection and whose prognosis is good.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Castleman病:两种变异，两名患者

castleman病(CD)是一种罕见的淋巴细胞增生性疾病，最常见于纵隔和腹部。本文描述了两例纵膈定位的乳糜泻。第一例发现于一名患有与霍奇金病相关的CD浆细胞变异的33岁女性，第二例发现于一名32岁的透明血管型CD的女性。病因不明的CD在临床上有两种形式，多中心，影响多个器官，发生一般症状，可伴有其他累及，如淋巴瘤。第二种是局部性，较常见，因质量效应而无症状发展或有压缩症状。在这些病例中，可以看到这种情况在其两种变体的临床表现的差异。结论scd是一种少见的淋巴细胞增生性疾病，治疗方法为肿瘤切除，预后良好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Revista de Patologia Respiratoria Medicine-Pulmonary and Respiratory Medicine

CiteScore

0.30

自引率

0.00%

发文量

期刊介绍： Revista de Patología Respiratoria is the scientific journal of the Madrilenian Pulmonology and Thoracic Surgery Society (Neumomadrid). It will consider those original articles related to Pulmonology, Thoracic Surgery and all other related sciences for their possible publication. Other types of articles such as reviews, editorials, special articles, scientific letters and letters to the editor are also published in the journal. It is a quarterly Journal that publishes a total of 4 issues, which contain these types of articles to different extents. All publications submitted will always undergo a peer review and a final decision will be made according to comments from the expert reviewers and members of the Editorial Board. The Journal is published both in Spanish and English. Therefore, the submission of manuscripts written in either Spanish or English is welcome.