Intervención coronaria en pacientes con fibrilación auricular

Carlos Minguito Carazo , Tomás Benito-González , Armando Pérez de Prado , Felipe Fernández-Vázquez
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Abstract

Patients with atrial fibrillation and coronary artery disease often have an elevated risk of both ischemia and bleeding. In the context of oral anticoagulation, clopidogrel is the P2Y12 inhibitor with the best safety profile. However, although it is recommended for patients with acute coronary syndromes, there is still some debate today about whether it should be used for pretreatment before invasive procedures. In patients scheduled to undergo an elective percutaneous coronary intervention, heparin bridging before the procedure is not recommended because this approach has been associated with an increased incidence of adverse events. Radial access should be preferred in the majority of cases when hemodynamics and the coronary anatomy permit. Although the evidence is still limited, it is recommended that low-dose unfractionated heparin should be administered during the procedure.

Supplement information: this article is part of a supplement entitled “Treatment of patients with atrial fibrillation undergoing percutaneous coronary intervention: an update”, which is sponsored by Boehringer Ingelheim.

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心房颤动患者的冠状动脉干预
心房颤动和冠状动脉疾病的患者往往有缺血和出血的高风险。在口服抗凝方面,氯吡格雷是最安全的P2Y12抑制剂。然而,尽管它被推荐用于急性冠状动脉综合征患者,但目前仍有一些关于是否应该在侵入性手术前用于预处理的争论。在计划接受择期经皮冠状动脉介入治疗的患者中,不建议在手术前使用肝素桥接,因为这种方法与不良事件的发生率增加有关。在血流动力学和冠状动脉解剖允许的情况下,大多数情况下首选桡动脉通路。尽管证据仍然有限,但建议在手术过程中使用低剂量的未分离肝素。补充信息:本文是由勃林格殷格翰公司赞助的题为“经皮冠状动脉介入治疗心房颤动患者:最新进展”的补充文章的一部分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Revista Espanola de Cardiologia Suplementos
Revista Espanola de Cardiologia Suplementos Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.20
自引率
0.00%
发文量
1
期刊介绍: Revista Española de Cardiología, is an international scientific journal dealing with cardiovascular medicine. Revista Española de Cardiología, the official publication of the Spanish Society of Cardiology, publishes research articles related to cardiovascular diseases. Articles are published in Spanish for the paper edition and in both Spanish and English in the electronic edition, which is available on the Internet. Regular sections include original articles reporting clinical or basic research, brief reports, review articles, editorials and letters to the Editor.
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