Pregnancy management decisions by adolescents following second-trimester prenatal diagnosis of fetal abnormalities

L.P. Shulman M.D., O.P. Phillips M.D., D. Muram M.D., S. Elias M.D.
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Abstract

Study Objective: To evaluate the pregnancy management decisions made by adolescents who were found to be carrying fetuses with abnormalities.

Design: Adolescent women who were carrying fetuses with abnormalities detected in the second trimester of pregnancy were evaluated as to their decision to continue or terminate their pregnancies. The decision by these women to include parents, guardians, or partners in the counseling process was also evaluated.

Setting: The clinical offices of the Division of Reproductive Genetics, Department of Obstetrics and Gynecology, University of Tennessee, Memphis.

Participants: Twelve adolescent women (16 years old or younger) who were found to be carrying fetuses with abnormalities. All participants were between 14 and 20 weeks gestation.

Main Outcome Measures: Genetic counseling was provided to five women carrying fetuses with chromosome abnormalities (two trisomy 21, two 45,X, and one trisomy 13), four women with fetuses demonstrating malformations with normal chromosome complements, and three women carrying fetuses with neural tube defects (two spina bifida and one anencephaly).

Results: All 12 women elected to have a parent or guardian accompany them for genetic counseling following the detection of fetal abnormalities. In five cases the patient's partner attended the counseling session. All women elected to terminate their pregnancies.

Conclusion: Factors other than severity of the abnormality (e.g., desire to terminate the pregnancy irrespective of abnormality, stable and nurturing marital or family relationships, economic independence) may play important roles in the adolescents' decision to continue or terminate a pregnancy after detection of fetal abnormalities.

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妊娠中期产前胎儿异常诊断后青少年的妊娠管理决策
研究目的:评价发现携带异常胎儿的青少年的妊娠管理决策。设计:对怀孕中期发现胎儿异常的青春期妇女进行评估,以决定继续或终止妊娠。这些妇女在咨询过程中让父母、监护人或伴侣参与的决定也被评估。地点:田纳西大学孟菲斯分校妇产科生殖遗传学部临床办公室。参与者:12名被发现携带异常胎儿的青春期女性(16岁或以下)。所有参与者的孕期都在14到20周之间。主要观察指标:对5例染色体异常胎儿(2例21三体,2例45三体,2例X三体,1例13三体),4例染色体互补正常的畸形胎儿,3例神经管缺陷胎儿(2例脊柱裂,1例无脑畸形)进行遗传咨询。结果:所有12名妇女在发现胎儿异常后均选择由父母或监护人陪同进行遗传咨询。在五个案例中,患者的伴侣参加了咨询会议。所有妇女都选择终止妊娠。结论:除异常严重程度以外的其他因素(例如,不考虑异常而终止妊娠的愿望,稳定和培育的婚姻或家庭关系,经济独立)可能在发现胎儿异常后青少年决定继续或终止妊娠方面发挥重要作用。
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