M.A. Vardar M.D. , H. Zeren M.D. , C. Demir M.D. , C. Evrüke M.D. , N. Özpoyraz M.D. , O. Kadayifçi M.D. , A. Altintaş M.D. , S. Zorludemir M.D.
{"title":"Testicular dysgenesis and mental retardation in two siblings with male pseudohermaphroditism","authors":"M.A. Vardar M.D. , H. Zeren M.D. , C. Demir M.D. , C. Evrüke M.D. , N. Özpoyraz M.D. , O. Kadayifçi M.D. , A. Altintaş M.D. , S. Zorludemir M.D.","doi":"10.1016/S0932-8610(19)80005-1","DOIUrl":null,"url":null,"abstract":"<div><p>Two mentally disabled phenotypic females, 46,XY dysgonadal sisters from a consanguineous marriage are described. Low plasma testosterone levels and an inadequate response of plasma-testosterone to human chorionic gonadotrophin (hCG) stimulation were noted in both cases. Dysgenetic testes and remnants of the müllerian and wolffian ducts were identified at exploratory laparotomy. Mild mental retardation was also present in both cases. These data may suggest the specific role of genetic factors in the etiology of testicular dysgenesis.</p></div>","PeriodicalId":80358,"journal":{"name":"Adolescent and pediatric gynecology","volume":"8 3","pages":"Pages 132-134"},"PeriodicalIF":0.0000,"publicationDate":"1995-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0932-8610(19)80005-1","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Adolescent and pediatric gynecology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0932861019800051","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Two mentally disabled phenotypic females, 46,XY dysgonadal sisters from a consanguineous marriage are described. Low plasma testosterone levels and an inadequate response of plasma-testosterone to human chorionic gonadotrophin (hCG) stimulation were noted in both cases. Dysgenetic testes and remnants of the müllerian and wolffian ducts were identified at exploratory laparotomy. Mild mental retardation was also present in both cases. These data may suggest the specific role of genetic factors in the etiology of testicular dysgenesis.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
