Vibha Mishra, S. N. Pandeya, Christophe Pannecouque, Myriam Witvrouw, E. De Clercq
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引用次数: 60
Abstract
A series of thiosemicarbazones and semicarbazone derivatives of (±)-3-menthone have been synthesized and their anti-HIV activity evaluated against HIV-1(IIIB)and HIV-2 (ROD). The studies revealed that maximum protection is offered by chloro-substituted derivatives 2 and 7 against HIV-1 (IIIB) and HIV-2 (ROD).
期刊介绍:
Archiv der Pharmazie - Chemistry in Life Sciences is an international journal devoted to research and development in all fields of pharmaceutical and medicinal chemistry. Emphasis is put on papers combining synthetic organic chemistry, structural biology, molecular modelling, bioorganic chemistry, natural products chemistry, biochemistry or analytical methods with pharmaceutical or medicinal aspects such as biological activity. The focus of this journal is put on original research papers, but other scientifically valuable contributions (e.g. reviews, minireviews, highlights, symposia contributions, discussions, and essays) are also welcome.