Eradicating Helicobacter pylori in patients with a past history of peptic ulcer: Is the juice worth the squeeze?

Journal of quality in clinical practice Pub Date : 2002-01-12 DOI:10.1046/j.1440-1762.2001.00410.x

Anne Duggan PhD, MHP, FRACP, Jas Bilku MBChB, FRCGP, Keith Ledger BM, BCh, Robert Scaffardi BM, BCh, Christopher J Hawkey DM, FRCP

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引用次数: 3

Abstract The efficacy of Helicobacter pylori eradication for H. pylori associated duodenal ulcer disease is beyond dispute. However, little attention has been paid to how feasible it is in primary care to undertake H. pylori eradication for patients with a past history of peptic ulcer disease. Patients identified by computer search of three general practices with a documented history of peptic ulcer disease were invited to attend for H. pylori testing and eradication therapy if H. pylori positive. A total of 101 patients were identified from a combined practice size of 24 780 of whom 34 were eligible for testing. Twenty-one per cent (seven patients) declined testing, 3% (one patient) refused therapy and another 21% (seven patients) were H. pylori negative. Helicobacter pylori eradication was highly successful (95%) and had an effect on prescription and reconsultation rates at 12 months. Eradicating H. pylori in patients with a past history of peptic ulcer disease not associated with non-steroidal anti-inflammatory drug ingestion is a challenging goal in general practice.

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消化性溃疡病史患者的幽门螺杆菌根除:果汁值得压榨吗?

摘要幽门螺杆菌根除治疗幽门螺杆菌相关十二指肠溃疡的疗效无可争议。然而，很少有人注意到在初级保健中对有消化性溃疡病史的患者进行幽门螺杆菌根除的可行性。通过计算机搜索三个有消化性溃疡病史的全科医生，邀请患者参加幽门螺杆菌检测和根除治疗，如果幽门螺杆菌阳性。从24780例患者中共确定101例患者，其中34例符合检测条件。21%(7名患者)拒绝检测，3%(1名患者)拒绝治疗，另有21%(7名患者)幽门螺杆菌阴性。幽门螺杆菌根除非常成功(95%)，并对12个月的处方和复诊率有影响。根除消化性溃疡病史与非甾体抗炎药摄入无关的幽门螺杆菌在一般实践中是一个具有挑战性的目标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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