{"title":"Malonaldehyde Synthesis","authors":"A. Trivella, S. Coussan, T. Chiavassa","doi":"10.1080/00397910802122433","DOIUrl":null,"url":null,"abstract":"Abstract Pure malonaldehyde is obtained by organic synthesis. In the first step, malonaldehyde sodium salt is obtained by 1,1,3,3-tetramethoxypropane acidic hydrolysis and purified by recrystallization in methanol/ether. In the second step, malonaldehyde is synthesized by reaction between malonaldehyde sodium salt and gaseous hydrochloric acid dissolved in ether at − 40 °C. Finally, malonaldehyde is purified by pumping at temperatures less than 0 °C and extracted by sublimation.","PeriodicalId":22119,"journal":{"name":"Synthetic Communications","volume":"38 1","pages":"3285 - 3290"},"PeriodicalIF":1.8000,"publicationDate":"2008-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00397910802122433","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthetic Communications","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/00397910802122433","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 1
Abstract
Abstract Pure malonaldehyde is obtained by organic synthesis. In the first step, malonaldehyde sodium salt is obtained by 1,1,3,3-tetramethoxypropane acidic hydrolysis and purified by recrystallization in methanol/ether. In the second step, malonaldehyde is synthesized by reaction between malonaldehyde sodium salt and gaseous hydrochloric acid dissolved in ether at − 40 °C. Finally, malonaldehyde is purified by pumping at temperatures less than 0 °C and extracted by sublimation.
期刊介绍：
Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.
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