Family Building in Transgender Patients: Modern Strategies with Assisted Reproductive Technology Treatment.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-01-31 eCollection Date: 2024-02-01 DOI:10.1089/trgh.2021.0210
Atoosa Ghofranian, Devora Aharon, Jenna Friedenthal, William J Hanley, Joseph A Lee, Margaret Daneyko, Zoe Rodriguez, Joshua D Safer, Alan B Copperman
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Abstract

Purpose: Transgender and gender diverse (TGD) individuals continue to face adversity, stigma, and inequality, especially in health care. This study aimed to characterize the experience of TGD people and partners of TGD people with regard to fertility treatment.

Methods: All TGD patients presenting to a single academic center between 2013 and 2021 were included. Baseline demographics collected included patient age, body mass index, anti-Mullerian hormone, basal antral follicle count, history of gender-affirming surgery, and/or gender-affirming hormone therapy. Outcomes included total patients who progressed to treatment, cycle type(s), and clinical outcomes.

Results: In total, 82 patients who identified as TGD or had a partner who identified as TGD presented to care seeking fertility treatment. Of the 141 planned cycles, 106 (75.2%) progressed to treatment. Of the 15 in vitro fertilization (IVF) and co-IVF cycles, 12 achieved live birth. Of the 76 intrauterine inseminations 7 patients were discharged with ongoing pregnancies and one achieved live birth.

Conclusion: These findings reaffirm that TGD individuals utilize the entire array of fertility services. With recent advances in access to care and modern medicine, assisted reproductive technology treatment has the power to support TGD patients in building contemporary family structures.

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变性患者的家庭建设:辅助生殖技术治疗的现代策略。
目的:跨性别者和性别多元化者(TGD)仍然面临着逆境、耻辱和不平等,尤其是在医疗保健方面。本研究旨在了解跨性别者及其伴侣在生育治疗方面的经历:研究纳入了2013年至2021年间在一家学术中心就诊的所有TGD患者。收集的基线人口统计数据包括患者年龄、体重指数、抗穆勒里激素、基础前卵泡计数、性别确认手术史和/或性别确认激素治疗史。结果包括接受治疗的患者总数、周期类型和临床结果:共有 82 名确认为 TGD 或其伴侣确认为 TGD 的患者前来寻求生育治疗。在 141 个计划周期中,106 个(75.2%)进入治疗阶段。在 15 个体外受精(IVF)和联合体外受精周期中,有 12 个实现了活产。在 76 例宫腔内人工授精中,有 7 例患者怀孕出院,1 例活产:这些研究结果再次证明,TGD 患者可以利用各种生育服务。随着近年来医疗服务和现代医学的进步,辅助生殖技术治疗能够帮助 TGD 患者建立现代家庭结构。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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