Topic category: Rehabilitation
A. Pelle, S. Pedersen, R. Erdman, Marquita, Spiering, M. Kazemier, J. Denollet, E. Skobel, P. Redanz, S. Schenk, O. Henssen, A. Jendralski, E. Marco, A. Robles, V. Arias, P. Cabero, M. Batlló, F. Escalada, J. Bruguera
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{"title":"Topic category: Rehabilitation","authors":"A. Pelle, S. Pedersen, R. Erdman, Marquita, Spiering, M. Kazemier, J. Denollet, E. Skobel, P. Redanz, S. Schenk, O. Henssen, A. Jendralski, E. Marco, A. Robles, V. Arias, P. Cabero, M. Batlló, F. Escalada, J. Bruguera","doi":"10.1097/01.hjr.0000244578.40723.de","DOIUrl":null,"url":null,"abstract":"Topic category: Rehabilitation European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S78–S104 019 RCT of a cognitive-behavioural programme for people awaiting CABGS G. Furze, K. Irvine, J.C. Dumville, J.N.V. Miles, D.R. Thompson, R.J.P. Lewin University of York, York, United Kingdom Cardiothoracic Centre, Hull and East Yorkshire Hospitals NHS Trust, Hull, United Kingdom University of Leicester, Leicester, United Kingdom Objectives The aim of this study was to develop and assess through a randomised controlled trial the ‘‘HeartOp Programme’’, a brief, cognitive-behavioural home-based rehabilitation programme for people waiting for coronary artery bypass graft surgery (CABGS). It was designed to help patients maintain or improve their activity levels and quality of life. Nurse counselling and contact by phone calls during the wait period had already been shown to be effective in improving quality of life so we randomised patients to either the HeartOp Programme or to nurse counselling with written educational materials and regular phone contact. Methods A randomised controlled trial (RCT) of 204 people recruited at entry to the waiting list for first time CABGS. All received a 4560 minute interview with a nurse and phone follow-up at weeks 1, 3 and 6. In addition the 104 control patients received British Heart Foundation booklets about their condition. The 100 intervention patients received the HeartOp Programme. Questionnaire measures (including economic data) were collected prior to randomisation (T1) and after 8 weeks (T2). Primary endpoints were: anxiety (State Trait Anxiety Inventory) and length of hospital stay. Secondary endpoints were: depression (Cardiac Depression Scale), physical functioning (Cardiac Limitations and Symptoms Profile (CLASP) Mobility Scale), misconceptions (Cardiac Beliefs Questionnaire) and cost utility (EQ5D). Data were analysed using intention to treat by analysis of covariance controlling for T1 medical and risk factor variables and the T1 measure of the T2 outcome variable. Results Post-intervention there were no differences between groups in the primary endpoints of anxiety or length of hospital stay. There were significant differences in the secondary endpoints of scores for: depression (difference = 7.79, p = 0.008, 95% CI = 2.04-13.54), physical functioning (difference = 0.82, p = 0.001, 95% CI = 0.34-1.3) and cardiac beliefs (difference = 2.56, p < 0.001, 95% CI = 1.64-3.48) in favour of the HeartOp Programme. The economic analysis suggests that the intervention is likely to be cost effective if implemented. Conclusions The HeartOp home-based cardiac rehabilitation programme appears to add worthwhile and cost effective benefits to a regime of nurse counselling and phone calls. It therefore can be recommended as an additional tool for nurses working with CABG patients in the pre-surgery period. 044 Women participating in phase 3 cardiac cehabilitation: a comparison between mixed and female only exercise groups? Shirley Ingram, Noeleen Fallon, Nora Flynn, Caroline Finn, Joan Love Cardiac Rehabilitation Dept Adelaide & Meath Hospital, Dublin, Ireland shirley.ingram@amnch.ie Introduction The natural course of coronary heart disease (CHD) is different for males’ and females. Women were not included in the early cardiac rehabilitation (CR) trials but respond as favourably as men to CR., however women are less likely to be referred to CR and once referred less likely to attend. The number of female participants in CR programmes ranges between 4.4% and 11%. Aim It has been suggested that tailoring CR programmes to women may increase participation. The aim of this study was to compare variables between women who attended female only phase 3 exercise groups to women who attended phase 3 in groups with males. Methodology Women who had agreed to participate in phase 3 were randomly assigned to mixed v female only phase 3 exercise groups. Outcome measurements included attendance, compliance, Hospital Anxiety and Depression scale (HADS), and Duke Activity Status Index (DASI) upon commencement and post cardiac rehabilitation. Paired t tests were used to compare scores pre and post treatment. Results A total of 78 women were offered Phase 3 CR between March 2005 & March 2006. Thirty five women accepted places in the female only group (FO), and 43 in the mixed group (FM). When compliance was analysed for the 2 groups there was 63% compliance in both groups. There was a decrease in anxiety scores for all after cardiac rehab (p < 0.0001). There was no significant difference in the decrease in anxiety scores between women who attended same sex groups and women who attended mixed groups (p = 0.1798). There was a decrease in depression scores for all at the end of cardiac rehab (p < 0.0001). There was no significant difference in the decrease in depression scores between groups (p = 0.1056). There was an increase in METS scores after rehab sessions (p < 0.0001). There was no significant difference in the increase in METS scores between women who attended same sex groups and women who attended mixed groups (p = 0.2429). Discussion There appears to be a good take up of Phase 3 CR amongst women (62.8%) in this centre compared with other research and being in a female only group does not appear to affect this. There are benefits in reduction in anxiety & depression & increases in MET activity for all women who completed this programme with no significant differences between groups. 051 Favourable effects of exercise-based cardiac rehabilitation on left atrial remodeling in postinfarction patients with moderate systolic dysfunction F. Giallauria, R. Lucci, A. De Lorenzo, M. Psaroudaki, S. Moschella, M. D’Agostino, D. Del Forno, C. Vigorito Department of Clinical Medicine, Cardiovascular and Immunological Sciences. Cardiac Rehabilitation Unit, University of Naples ‘‘Federico II’’, Naples (Italy) Objectives Left atrial (LA) enlargement is an important predictor of cardiovascular outcomes in patients after acute myocardial infarction (AMI). While the favourable effect of exercise based Cardiac Rehabilitation (CR) on postinfarction left ventricular (LV) remodeling have been well documented, those on LA remodeling has yet to be defined. This study investigated the effects of exercise-based CR on LA remodeling in postinfarction patients with moderate left ventricular (LV) dysfunction. Methods Sixty postinfarction patients were randomized into two groups, each composed of 30 patients: group T (LV ejection fraction (EF) 43.7 ± 4.2%, mean ± SD) entered a 6-month CR programme, whereas group C (EF 44.2 ± 3.6%, p = NS) did not. Doppler-echocardiography, 1741-8267 c 2007 The European Society of Cardiology Copyright © European Society of Cardiology. Unauthorized reproduction of this article is prohibited. cardiopulmonary exercise test and NT-proBNP assay were performed upon enrolment and at 6-month. Results At 6-month, trained patients showed an improvement in maximal oxygen consumption ( +32%, p < 0.001) and a reduction in LA ( – 6%, p < 0.001) and LV end-diastolic volumes ( – 9%, p < 0.001) and in NT-proBNP ( – 67%, p < 0.001). In trained patients, LA volume changes correlated with LVEDV (r = 0.479, p < 0.01) and NT-proBNP changes (r = 0.564, p < 0.01). In group T patients, we observed a significant correlation between 6-month NT-proBNP and E/A ratio changes (r = – 0.664, p < 0.0001). Untrained patients showed at 6 months (p < 0.001) and LV dilation ( + 9%, p < 0.001; T vs C group, p < 0.001) and a smaller reduction in NT-proBNP ( – 38%, p < 0.001; T vs C group, p < 0.001). Conclusions Six-month exercise-based CR in postinfarction patients with moderate LV dysfunction induced a favourable LA remodeling. LA volume could emerge as a simple and important tool for risk stratification and as a guide for future evaluation and therapeutic interventions in postinfarction patients. 052 Importance of exercise testing protocol for detecting training effects in cardiac patients D. Hansen, P. Dendale, J. Berger, R. Meeusen Vrije Universiteit Brussel, Dept. Human Physiology and Sportsmedicine, Brussels, Belgium Virga Jesse Hospital, Rehabilitation and Health Centre, Hasselt, Belgium Objectives In cardiac rehabilitation, determining changes of peak oxygen uptake (VO2peak) is important. For this determination, exercise testing protocols with one-minute or three-minute stages can be used. Nonetheless, it is not known which protocol is most sensitive for assessing VO2peak changes as result of exercise training in cardiac patients. Methods 42 cardiac patients (mean age 65.4 ± 8.4 years, 33 males) were included into a cardiac rehabilitation programme and randomised in two subgroups. One group of patients was evaluated by a one-minute stage (n = 21) and another group by a three-minute stage (n = 21) exercise testing protocol. In both groups, maximal cardiopulmonary exercise tests on bike with analysis of oxygen uptake (VO2), expiratory volume (VE), respiratory exchange ratio (RER), heart rate (HR), cycling resistance (W) and test duration were executed at the start and end of the programme. Results Subgroups were closely matched and no changes of betablocker treatment occurred during this study. As result of the rehabilitation programme, total test duration and Wpeak improved significantly in both groups (p < 0.05). Nonetheless, VO2peak and VEpeak increased significantly in the one-minute stage duration group (p < 0.05), but not in the three-minute stage duration group (p > 0.05). In addition, change of VO2peak, VEpeak, and total test duration was significantly greater in the one-minute stage duration group, as compared to the three-minute stage duration group (p < 0.05). Conclusion For detecting changes of VO2peak as result of exercise training in cardiac patients, a one-minute stage exercise testing protocol is more sensitive as compared to a three-minute stage exercise testing protocol. 058 Can we of","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"14 1","pages":"S104 - S78"},"PeriodicalIF":0.0000,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000244578.40723.de","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Cardiovascular Prevention & Rehabilitation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/01.hjr.0000244578.40723.de","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Topic category: Rehabilitation European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S78–S104 019 RCT of a cognitive-behavioural programme for people awaiting CABGS G. Furze, K. Irvine, J.C. Dumville, J.N.V. Miles, D.R. Thompson, R.J.P. Lewin University of York, York, United Kingdom Cardiothoracic Centre, Hull and East Yorkshire Hospitals NHS Trust, Hull, United Kingdom University of Leicester, Leicester, United Kingdom Objectives The aim of this study was to develop and assess through a randomised controlled trial the ‘‘HeartOp Programme’’, a brief, cognitive-behavioural home-based rehabilitation programme for people waiting for coronary artery bypass graft surgery (CABGS). It was designed to help patients maintain or improve their activity levels and quality of life. Nurse counselling and contact by phone calls during the wait period had already been shown to be effective in improving quality of life so we randomised patients to either the HeartOp Programme or to nurse counselling with written educational materials and regular phone contact. Methods A randomised controlled trial (RCT) of 204 people recruited at entry to the waiting list for first time CABGS. All received a 4560 minute interview with a nurse and phone follow-up at weeks 1, 3 and 6. In addition the 104 control patients received British Heart Foundation booklets about their condition. The 100 intervention patients received the HeartOp Programme. Questionnaire measures (including economic data) were collected prior to randomisation (T1) and after 8 weeks (T2). Primary endpoints were: anxiety (State Trait Anxiety Inventory) and length of hospital stay. Secondary endpoints were: depression (Cardiac Depression Scale), physical functioning (Cardiac Limitations and Symptoms Profile (CLASP) Mobility Scale), misconceptions (Cardiac Beliefs Questionnaire) and cost utility (EQ5D). Data were analysed using intention to treat by analysis of covariance controlling for T1 medical and risk factor variables and the T1 measure of the T2 outcome variable. Results Post-intervention there were no differences between groups in the primary endpoints of anxiety or length of hospital stay. There were significant differences in the secondary endpoints of scores for: depression (difference = 7.79, p = 0.008, 95% CI = 2.04-13.54), physical functioning (difference = 0.82, p = 0.001, 95% CI = 0.34-1.3) and cardiac beliefs (difference = 2.56, p < 0.001, 95% CI = 1.64-3.48) in favour of the HeartOp Programme. The economic analysis suggests that the intervention is likely to be cost effective if implemented. Conclusions The HeartOp home-based cardiac rehabilitation programme appears to add worthwhile and cost effective benefits to a regime of nurse counselling and phone calls. It therefore can be recommended as an additional tool for nurses working with CABG patients in the pre-surgery period. 044 Women participating in phase 3 cardiac cehabilitation: a comparison between mixed and female only exercise groups? Shirley Ingram, Noeleen Fallon, Nora Flynn, Caroline Finn, Joan Love Cardiac Rehabilitation Dept Adelaide & Meath Hospital, Dublin, Ireland shirley.ingram@amnch.ie Introduction The natural course of coronary heart disease (CHD) is different for males’ and females. Women were not included in the early cardiac rehabilitation (CR) trials but respond as favourably as men to CR., however women are less likely to be referred to CR and once referred less likely to attend. The number of female participants in CR programmes ranges between 4.4% and 11%. Aim It has been suggested that tailoring CR programmes to women may increase participation. The aim of this study was to compare variables between women who attended female only phase 3 exercise groups to women who attended phase 3 in groups with males. Methodology Women who had agreed to participate in phase 3 were randomly assigned to mixed v female only phase 3 exercise groups. Outcome measurements included attendance, compliance, Hospital Anxiety and Depression scale (HADS), and Duke Activity Status Index (DASI) upon commencement and post cardiac rehabilitation. Paired t tests were used to compare scores pre and post treatment. Results A total of 78 women were offered Phase 3 CR between March 2005 & March 2006. Thirty five women accepted places in the female only group (FO), and 43 in the mixed group (FM). When compliance was analysed for the 2 groups there was 63% compliance in both groups. There was a decrease in anxiety scores for all after cardiac rehab (p < 0.0001). There was no significant difference in the decrease in anxiety scores between women who attended same sex groups and women who attended mixed groups (p = 0.1798). There was a decrease in depression scores for all at the end of cardiac rehab (p < 0.0001). There was no significant difference in the decrease in depression scores between groups (p = 0.1056). There was an increase in METS scores after rehab sessions (p < 0.0001). There was no significant difference in the increase in METS scores between women who attended same sex groups and women who attended mixed groups (p = 0.2429). Discussion There appears to be a good take up of Phase 3 CR amongst women (62.8%) in this centre compared with other research and being in a female only group does not appear to affect this. There are benefits in reduction in anxiety & depression & increases in MET activity for all women who completed this programme with no significant differences between groups. 051 Favourable effects of exercise-based cardiac rehabilitation on left atrial remodeling in postinfarction patients with moderate systolic dysfunction F. Giallauria, R. Lucci, A. De Lorenzo, M. Psaroudaki, S. Moschella, M. D’Agostino, D. Del Forno, C. Vigorito Department of Clinical Medicine, Cardiovascular and Immunological Sciences. Cardiac Rehabilitation Unit, University of Naples ‘‘Federico II’’, Naples (Italy) Objectives Left atrial (LA) enlargement is an important predictor of cardiovascular outcomes in patients after acute myocardial infarction (AMI). While the favourable effect of exercise based Cardiac Rehabilitation (CR) on postinfarction left ventricular (LV) remodeling have been well documented, those on LA remodeling has yet to be defined. This study investigated the effects of exercise-based CR on LA remodeling in postinfarction patients with moderate left ventricular (LV) dysfunction. Methods Sixty postinfarction patients were randomized into two groups, each composed of 30 patients: group T (LV ejection fraction (EF) 43.7 ± 4.2%, mean ± SD) entered a 6-month CR programme, whereas group C (EF 44.2 ± 3.6%, p = NS) did not. Doppler-echocardiography, 1741-8267 c 2007 The European Society of Cardiology Copyright © European Society of Cardiology. Unauthorized reproduction of this article is prohibited. cardiopulmonary exercise test and NT-proBNP assay were performed upon enrolment and at 6-month. Results At 6-month, trained patients showed an improvement in maximal oxygen consumption ( +32%, p < 0.001) and a reduction in LA ( – 6%, p < 0.001) and LV end-diastolic volumes ( – 9%, p < 0.001) and in NT-proBNP ( – 67%, p < 0.001). In trained patients, LA volume changes correlated with LVEDV (r = 0.479, p < 0.01) and NT-proBNP changes (r = 0.564, p < 0.01). In group T patients, we observed a significant correlation between 6-month NT-proBNP and E/A ratio changes (r = – 0.664, p < 0.0001). Untrained patients showed at 6 months (p < 0.001) and LV dilation ( + 9%, p < 0.001; T vs C group, p < 0.001) and a smaller reduction in NT-proBNP ( – 38%, p < 0.001; T vs C group, p < 0.001). Conclusions Six-month exercise-based CR in postinfarction patients with moderate LV dysfunction induced a favourable LA remodeling. LA volume could emerge as a simple and important tool for risk stratification and as a guide for future evaluation and therapeutic interventions in postinfarction patients. 052 Importance of exercise testing protocol for detecting training effects in cardiac patients D. Hansen, P. Dendale, J. Berger, R. Meeusen Vrije Universiteit Brussel, Dept. Human Physiology and Sportsmedicine, Brussels, Belgium Virga Jesse Hospital, Rehabilitation and Health Centre, Hasselt, Belgium Objectives In cardiac rehabilitation, determining changes of peak oxygen uptake (VO2peak) is important. For this determination, exercise testing protocols with one-minute or three-minute stages can be used. Nonetheless, it is not known which protocol is most sensitive for assessing VO2peak changes as result of exercise training in cardiac patients. Methods 42 cardiac patients (mean age 65.4 ± 8.4 years, 33 males) were included into a cardiac rehabilitation programme and randomised in two subgroups. One group of patients was evaluated by a one-minute stage (n = 21) and another group by a three-minute stage (n = 21) exercise testing protocol. In both groups, maximal cardiopulmonary exercise tests on bike with analysis of oxygen uptake (VO2), expiratory volume (VE), respiratory exchange ratio (RER), heart rate (HR), cycling resistance (W) and test duration were executed at the start and end of the programme. Results Subgroups were closely matched and no changes of betablocker treatment occurred during this study. As result of the rehabilitation programme, total test duration and Wpeak improved significantly in both groups (p < 0.05). Nonetheless, VO2peak and VEpeak increased significantly in the one-minute stage duration group (p < 0.05), but not in the three-minute stage duration group (p > 0.05). In addition, change of VO2peak, VEpeak, and total test duration was significantly greater in the one-minute stage duration group, as compared to the three-minute stage duration group (p < 0.05). Conclusion For detecting changes of VO2peak as result of exercise training in cardiac patients, a one-minute stage exercise testing protocol is more sensitive as compared to a three-minute stage exercise testing protocol. 058 Can we of
主题类别:康复
主题分类:欧洲心血管疾病预防与康复杂志,2007,14(增刊1):S78-S104 019 . G. Furze, K. Irvine, J.C. Dumville, J.N.V. Miles, dr . Thompson, R.J.P. Lewin .英国莱斯特大学赫尔大学和东约克郡医院NHS信托基金,赫尔大学莱斯特大学本研究的目的是通过一项随机对照试验来开发和评估“HeartOp计划”,这是一项针对等待冠状动脉搭桥手术(CABGS)的患者的简短、认知-行为家庭康复计划。它旨在帮助患者维持或改善他们的活动水平和生活质量。在等待期间,护士咨询和电话联系已经被证明对改善生活质量是有效的,因此我们将患者随机分为两组,一组是HeartOp项目,另一组是提供书面教育材料和定期电话联系的护士咨询。方法采用随机对照试验(RCT),纳入204例首次行CABGS的患者。在第1周、第3周和第6周,所有人都接受了4560分钟的护士访谈和电话随访。此外,104名对照患者收到了英国心脏基金会关于他们病情的小册子。100名干预患者接受了hearttop计划。在随机化之前(T1)和8周后(T2)收集问卷测量(包括经济数据)。主要终点是:焦虑(状态-特质焦虑量表)和住院时间。次要终点是:抑郁(心脏抑郁量表)、身体功能(心脏局限性和症状概况(CLASP)活动量表)、误解(心脏信念问卷)和成本效用(EQ5D)。采用意向治疗法对T1医疗和危险因素变量进行协方差分析,对T2结局变量进行T1测量。结果干预后,两组在焦虑或住院时间的主要终点上没有差异。评分的次要终点有显著差异:抑郁(差异= 7.79,p = 0.008, 95% CI = 2.04-13.54)、身体功能(差异= 0.82,p = 0.001, 95% CI = 0.34-1.3)和心脏信念(差异= 2.56,p < 0.001, 95% CI = 1.64-3.48)有利于HeartOp项目。经济分析表明,如果实施干预,可能具有成本效益。结论:hearttop家庭心脏康复方案似乎为护士咨询和电话治疗制度增加了有价值和成本效益的好处。因此,它可以被推荐为护士在术前与CABG患者一起工作的额外工具。参与3期心脏康复的女性:混合运动组和仅女性运动组的比较?Shirley Ingram, Noeleen Fallon, Nora Flynn, Caroline Finn, Joan Love心脏康复科阿德莱德&米斯医院,都柏林,爱尔兰shirley.ingram@amnch.ie介绍冠心病(CHD)的自然病程在男性和女性中是不同的。女性未被纳入早期心脏康复(CR)试验,但对CR的反应与男性一样好,然而女性被转介到CR的可能性较小,一旦转介到CR的可能性较小。女性参与企业社会责任项目的比例在4.4%至11%之间。目的:有人建议,为女性量身定制企业社会责任项目可能会提高参与率。这项研究的目的是比较参加第三阶段女性锻炼组和参加第三阶段男性锻炼组的女性之间的变量。同意参加第三阶段的妇女被随机分配到男女混合或只有女性的第三阶段运动组。结果测量包括开始和心脏康复时的出勤、依从性、医院焦虑和抑郁量表(HADS)和杜克活动状态指数(DASI)。配对t检验用于比较治疗前后的得分。结果2005年3月至2006年3月,共有78名妇女接受了第三期CR治疗。35名女性进入女性组(FO), 43名女性进入混合组(FM)。当对两组的依从性进行分析时,两组的依从性均为63%。心脏康复后,所有患者的焦虑评分均下降(p < 0.0001)。参加同性组的妇女和参加混合组的妇女在焦虑得分的下降方面没有显著差异(p = 0.1798)。在心脏康复结束时,所有患者的抑郁评分均下降(p < 0.0001)。两组间抑郁评分下降差异无统计学意义(p = 0.1056)。康复治疗后,METS评分增加(p < 0.0001)。 参加同性组的妇女和参加混合组的妇女在met评分的增加方面没有显著差异(p = 0.2429)。与其他研究相比,该研究中心的女性(62.8%)似乎对第三阶段CR有很好的接受程度,而且仅在女性群体中似乎并不影响这一点。所有完成该项目的女性在减少焦虑和抑郁以及增加MET活动方面都有好处,各组之间没有显著差异。[51]运动心脏康复对心肌梗死后中度收缩功能障碍患者左房重构的积极影响F. Giallauria, R. Lucci, A. De Lorenzo, M. Psaroudaki, S. Moschella, M. D 'Agostino, D. Del Forno, C. Vigorito临床医学,心血管与免疫科学。目的左心房(LA)扩大是急性心肌梗死(AMI)后患者心血管预后的重要预测指标。尽管基于运动的心脏康复(CR)对梗死后左室(LV)重构的有利影响已被充分证实,但对左室重构的有利影响尚未得到明确。本研究探讨了基于运动的CR对梗死后中度左心室功能障碍患者LA重塑的影响。方法60例梗死后患者随机分为两组,每组30例:T组(左室射血分数(EF) 43.7±4.2%,mean±SD)进入6个月的CR计划,C组(EF 44.2±3.6%,p = NS)未进入CR计划。多普勒超声心动图,1741-8267 c 2007欧洲心脏病学会版权©欧洲心脏病学会。未经授权,禁止转载本文。在入组时和6个月时进行心肺运动试验和NT-proBNP测定。结果6个月时,经过训练的患者最大耗氧量(+32%,p < 0.001)改善,LA (- 6%, p < 0.001)和左室舒张末期容积(- 9%,p < 0.001)降低,NT-proBNP (- 67%, p < 0.001)降低。在训练过的患者中,LA容积变化与LVEDV (r = 0.479, p < 0.01)和NT-proBNP变化相关(r = 0.564, p < 0.01)。在T组患者中,我们观察到6个月NT-proBNP与E/ a比值变化具有显著相关性(r = - 0.664, p < 0.0001)。未经训练的患者在6个月时显示(p < 0.001)左室扩张(+ 9%,p < 0.001;T组与C组相比,p < 0.001), NT-proBNP降低幅度较小(- 38%,p < 0.001;T组vs C组,p < 0.001)。结论:在中度左室功能障碍的梗死后患者中,6个月的基于运动的CR诱导了有利的左室重塑。LA容积可作为一种简单而重要的风险分层工具,并可作为梗死后患者未来评估和治疗干预的指导。052运动测试方案对检测心脏病患者训练效果的重要性D. Hansen, P. Dendale, J. Berger, R. Meeusen布鲁塞尔自由大学,人体生理学和运动医学系,比利时布鲁塞尔Virga Jesse医院,康复和健康中心,比利时Hasselt目的在心脏康复中,确定峰值摄氧量(VO2peak)的变化是重要的。为了确定这一点,可以使用一分钟或三分钟阶段的运动测试方案。尽管如此,对于评估心脏病患者运动训练导致的vo2峰值变化,尚不清楚哪种方案最敏感。方法将42例心脏病患者(平均年龄65.4±8.4岁,男性33例)纳入心脏康复计划,随机分为两个亚组。一组患者采用1分钟运动测试方案(n = 21),另一组采用3分钟运动测试方案(n = 21)。两组均在项目开始和结束时进行自行车最大心肺运动试验,分析摄氧量(VO2)、呼气量(VE)、呼吸交换比(RER)、心率(HR)、骑行阻力(W)和试验持续时间。结果亚组密切匹配,本研究期间β受体阻滞剂治疗未发生变化。康复治疗后,两组总测试时间和Wpeak均显著改善(p < 0.05)。然而,VO2peak和VEpeak在1分钟组显著升高(p < 0.05),而在3分钟组无显著升高(p < 0.05)。此外,1分钟组VO2peak、VEpeak和总测试时间的变化显著大于3分钟组(p < 0.05)。结论对于检测心脏病患者运动训练引起的VO2peak变化,1分钟阶段运动测试方案比3分钟阶段运动测试方案更灵敏。 我们能
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