{"title":"Design Automation for Synthetic Biological Systems","authors":"D. Densmore, S. Hassoun","doi":"10.1109/MDT.2012.2193370","DOIUrl":null,"url":null,"abstract":"Through principled engineering methods, synthetic biology aims to build specialized biological components that can be modularly composed to create complex systems. This article outlines bio-design automation using two complementary design approaches, bottom-up modular construction from biological primitives and pathway-based approaches. The article also highlights future challenges for both.","PeriodicalId":50392,"journal":{"name":"IEEE Design & Test of Computers","volume":"29 1","pages":"7-20"},"PeriodicalIF":0.0000,"publicationDate":"2012-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MDT.2012.2193370","citationCount":"23","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Design & Test of Computers","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MDT.2012.2193370","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 23
Abstract
Through principled engineering methods, synthetic biology aims to build specialized biological components that can be modularly composed to create complex systems. This article outlines bio-design automation using two complementary design approaches, bottom-up modular construction from biological primitives and pathway-based approaches. The article also highlights future challenges for both.