Distribution, regulation and role of the agmatine deiminase system in mutans streptococci.

Ann R. Griswold, Marcelle M. Nascimento, Robert A. Burne
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引用次数: 21

Abstract

The agmatine deiminase system (AgDS) was identified in seven strains of mutans streptococci. Genes encoding the AgDS of Streptococcus rattus FA-1 were sequenced and found to share homology with the agu genes of Streptococcus mutans UA159. With the exception of Streptococcus sobrinus, the AgDS of mutans streptococci appear to be sensitive to carbohydrate catabolite repression. Agmatine inhibited bacterial growth, suggesting that the AgDS degrades a deleterious substance into useful compounds.
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变异链球菌中胍丁胺脱亚胺酶系统的分布、调控和作用。
在7株变异链球菌中鉴定出agmatine脱亚胺酶系统(AgDS)。对家鼠链球菌FA-1的AgDS编码基因进行测序,发现其与变形链球菌UA159的agu基因具有同源性。除了sobrinus链球菌外,变形链球菌的AgDS似乎对碳水化合物分解代谢抑制敏感。Agmatine抑制细菌生长,表明AgDS将有害物质降解为有用的化合物。
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