Effects of xylazine/ketamine on cardiac function and serum ionised calcium in horses

T.L. Grubb , G.J. Benson , J.C. Thurmon , W.O. Olson , W.J. Tranquilli , J.H. Foreman , P.D. Constable , L.E. Davis
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引用次数: 5

Abstract

Haemodynamic variables, with emphasis on right ventricular (RV) contractility, were measured in horses prior to, during and following anaesthesia with xylazine/ketamine. In an attempt to elicit mechanisms of anaesthetic-induced alteration of myocardial function, serum ionised and total calcium concentrations were also measured. Xylazine caused decreased cardiac function, including RV contractility, that was not reversed immediately by ketamine but was insignificant from pre-anaesthetic baseline by recovery (45 min following induction). Serum ionised and total calcium concentrations did not change.

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噻嗪/氯胺酮对马心功能和血清离子钙的影响
血液动力学变量,重点是右心室(RV)收缩力,测量马之前,期间和之后的二甲肼/氯胺酮麻醉。为了引出麻醉诱导心肌功能改变的机制,还测量了血清电离钙和总钙浓度。氯胺酮不能立即逆转Xylazine引起的心功能下降,包括右心室收缩力下降,但在诱导后45分钟恢复时,与麻醉前基线相比没有明显差异。血清游离钙和总钙浓度没有变化。
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