{"title":"Temporary storage of fresh frozen plasma above −30°C has no negative impact on the quality of clotting factors and inhibitors","authors":"R. Moog, D. Knop, F. Wenzel","doi":"10.1111/J.1778-428X.2010.01129.X","DOIUrl":null,"url":null,"abstract":"SUMMARY \n \nFresh frozen plasma (FFP) should be stored at temperatures > −30°C according to national and international guidelines to maintain the stability of clotting factors and inhibitors. In the present report, FFP was accidentally stored at < −30°C due to icing of the freezer. To ensure the quality of the FFPs a battery of tests of clotting factors and inhibitors was performed. Our data demonstrate that temporary storage of FFP at temperature < −30°C does not negatively affect the quality of FFPs. The European requirement of 70% activity of factor VIII was met by all units.","PeriodicalId":90375,"journal":{"name":"Transfusion alternatives in transfusion medicine : TATM","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1778-428X.2010.01129.X","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transfusion alternatives in transfusion medicine : TATM","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/J.1778-428X.2010.01129.X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
SUMMARY
Fresh frozen plasma (FFP) should be stored at temperatures > −30°C according to national and international guidelines to maintain the stability of clotting factors and inhibitors. In the present report, FFP was accidentally stored at < −30°C due to icing of the freezer. To ensure the quality of the FFPs a battery of tests of clotting factors and inhibitors was performed. Our data demonstrate that temporary storage of FFP at temperature < −30°C does not negatively affect the quality of FFPs. The European requirement of 70% activity of factor VIII was met by all units.