On rat serum lipase. IV. The effect of various dietary fats.

Abstract

Several dietary fats were tested for their effect on the serum tributyrinase activity of adult male rats. Enzyme levels were significantly higher in rats subsisting on diets containing 23% of any of the fats which were tested, when compared with values for animals which were given a dietary concentration of 8% of the same fat. At the 8% level there were significant differences in tributyrinase activity which appeared to be associated with the fatty acid composition of the lipid. In order of decreasing effect on the serum enzyme at the 8% dietary test level the fats are listed as follows: Crisco, butter, cottonseed oil, linseed oil, corn oil, and olive oil. At the 23% dietary level there are fewer significant effects on the enzyme which could be due to the fatty acid content of the various lipids.