An Efficient One-Pot Synthesis of 1,8-Dioxodecahydroacridines Using Silica-Supported Polyphosphoric Acid (PPA-SiO2) under Solvent-Free Conditions

F. Moeinpour, A. Khojastehnezhad
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引用次数: 20

Abstract

Silica gel–supported polyphosphoric acid (PPA-SiO2) was found to be an efficient catalyst for the synthesis of 1,8-dioxodecahydroacridines via one-pot three-component condensation of aryl aldehydes, dimedone, and ammonium acetate or 4-methyl aniline in high yields, easy workup procedure and short period of times. The catalyst was separated by simple filtration and used in the reaction three times without any significant loss of its activity.
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无溶剂条件下二氧化硅负载多磷酸(PPA-SiO2)一锅高效合成1,8-二氧十二氢吖啶化合物
短句来源硅胶负载型聚磷酸(PPA-SiO2)是芳醛、二美酮、乙酸铵或4-甲基苯胺一锅三组分缩合合成1,8-二氧十二氢吖啶的有效催化剂,收率高,工艺简单,反应时间短。催化剂经简单过滤分离,三次使用,活性无明显损失。
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来源期刊
E-journal of Chemistry
E-journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-
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