{"title":"Patho-Epigenetics","authors":"J. Minárovits, H. Niller","doi":"10.1159/000354284","DOIUrl":null,"url":null,"abstract":"Patho-epigenetics is a new discipline dealing with the description of pathologic changes elicited by epigenetic dysregulation. Patho-epigenetic processes contribute to the development of both rare syndromes and diseases of high prevalence in human populations. In this short review, we summarize the basic epigenetic regulatory mechanisms in a nutshell and briefly outline how epigenetic reprogramming contributes to all forms of tumorigenesis and plays a role both in the initiation and progression of neoplasms.","PeriodicalId":90260,"journal":{"name":"Medical epigenetics","volume":"1 1","pages":"37 - 45"},"PeriodicalIF":0.0000,"publicationDate":"2013-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000354284","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical epigenetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000354284","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Patho-epigenetics is a new discipline dealing with the description of pathologic changes elicited by epigenetic dysregulation. Patho-epigenetic processes contribute to the development of both rare syndromes and diseases of high prevalence in human populations. In this short review, we summarize the basic epigenetic regulatory mechanisms in a nutshell and briefly outline how epigenetic reprogramming contributes to all forms of tumorigenesis and plays a role both in the initiation and progression of neoplasms.