Patho-Epigenetics

J. Minárovits, H. Niller
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引用次数: 2

Abstract

Patho-epigenetics is a new discipline dealing with the description of pathologic changes elicited by epigenetic dysregulation. Patho-epigenetic processes contribute to the development of both rare syndromes and diseases of high prevalence in human populations. In this short review, we summarize the basic epigenetic regulatory mechanisms in a nutshell and briefly outline how epigenetic reprogramming contributes to all forms of tumorigenesis and plays a role both in the initiation and progression of neoplasms.
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Patho-Epigenetics
病理表观遗传学是研究由表观遗传异常引起的病理变化的一门新兴学科。病理-表观遗传过程促进了罕见综合征和人群中高患病率疾病的发展。在这篇简短的综述中,我们简要地总结了基本的表观遗传调控机制,并简要概述了表观遗传重编程如何促进所有形式的肿瘤发生,并在肿瘤的发生和发展中发挥作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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