{"title":"Genetic Aspects of Plasma Lipoprotein and Cholesterol Metabolism in Nonhuman Primate Models of Atherosclerosis","authors":"K. Laber-Laird, L. Rudel","doi":"10.1159/000416894","DOIUrl":null,"url":null,"abstract":"For these reasons, monkeys are the most practical and valuable primate models for studying genetic and environmental influences on lipoprotein and cholesterol metabolism and atherosclerosis. The biggest drawbacks to the use of these primates as genetic models are: 1) the expense and complications of maintenance, and 2) the long gestation time and propensity to single births, factors which make genetic studies in monkeys infrequent and difficult","PeriodicalId":76182,"journal":{"name":"Monographs in human genetics","volume":"12 1","pages":"170-188"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000416894","citationCount":"8","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monographs in human genetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000416894","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 8
Abstract
For these reasons, monkeys are the most practical and valuable primate models for studying genetic and environmental influences on lipoprotein and cholesterol metabolism and atherosclerosis. The biggest drawbacks to the use of these primates as genetic models are: 1) the expense and complications of maintenance, and 2) the long gestation time and propensity to single births, factors which make genetic studies in monkeys infrequent and difficult
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