Oral Abstract Session: Epidemiology and sports cardiology

A. Hingorani, A. Jones, M. Charakida, D. Lawlor, Gd Smith, Sattar, J. Deanfield, C. Fischbacher, H. Brown, S. Capewell
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Abstract

295 Prevalence and clinical significance of aortic root dilatation in highly-trained, competitive athletes B Di Giacinto, E De Blasiis, FM Di Paolo, FM Quattrini, C Pisicchio, E Guerra, R Ciardo, A Pelliccia Institute of Sport Medicine and Science, CONI, Rome, Italy Topic: Sports cardiology Purpose: Prevalence, clinical significance, and long-term consequences of aortic root (AoR) dilatation in competitive athletes are not yet investigated. Our aim was to assess the distribution and determinants of AoR size in a large population of competitive athletes. Methods: AoR dimension were assessed by echocardiography in 2,361 athletes participating in 48 different sports. Of them, 44 were excluded because aortic structural abnormalities, such as bicuspid aortic valve, Marfan s Syndrome, aortic prosthesis. The remaining 2,317, including 1,300 (56%) males and 1,017 (44%) females were the study population. Arbitrary cut-off of =40 mm, according to #36th Bethesda Conference, was used as upper normal limits for AoR. Results: In males AoR was 32.2 2.7 mm (range 23-44) and the 95th percentile was 37 mm. In females AoR was 27.5 2.6 mm (20-36) and the 95th percentile was 32 mm.Multiple regression and covariance analysis showed AoR dimension largely explained by body surface area, left ventricular mass and age (R21⁄4 0.61), with type of sports participation having only a modest effect. The AoR was<40 mm in 2,300 athletes (99%), and = 40 mm in only 17 (1%), all male. In this subset, aortic dimension increased over a 8 5 year follow-up (40.9 1.3 to 42.9 3.6 mm; p <0.01), including 3 former athletes in whomAoR become dilated (to 50mm, 50mm and 48mm) after 15-16 years, in the absence of symptoms or evidence of systemic disease. Conclusion:Dilatation of the aortic root ( =40 mm) is rare in highly trained athletes and is not a consistent feature of‘‘athlete s heart’’. Longitudinal assessment in athletes with AoR =40 mm showed further dimensional increase, which occasionally was very marked. Selective restriction from most intense competitive sports may be indicated in these athletes to reduce the risk associated with accelerated aortic enlargement.
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口头文摘:流行病学和运动心脏病学
295高训练竞技运动员主动脉根扩张的患病率和临床意义B Di Giacinto, E De Blasiis, FM Di Paolo, FM Quattrini, C Pisicchio, E Guerra, R Ciardo, A peliccia运动医学与科学研究所,CONI, Rome, Italy题目:运动心脏病学目的:竞技运动员主动脉根(AoR)扩张的患病率、临床意义和长期后果尚未调查。我们的目的是评估大量竞技运动员AoR大小的分布和决定因素。方法:采用超声心动图对参加48项运动的2361名运动员进行AoR维度评估。其中因二尖瓣主动脉瓣、马凡氏综合征、主动脉假体等主动脉结构异常排除44例。其余2,317人,包括1,300名(56%)男性和1,017名(44%)女性为研究人群。根据#36 Bethesda会议,任意截断=40 mm作为AoR的正常上限。结果:男性AoR为32.2 ~ 2.7 mm(范围23 ~ 44),第95百分位为37 mm。女性AoR为27.5 - 2.6 mm(20-36),第95百分位为32 mm。多元回归和协方差分析显示,AoR维度主要由体表面积、左心室质量和年龄解释(R21 / 4 0.61),运动类型对AoR维度影响不大。2300名运动员(99%)AoR <40 mm,只有17名(1%)运动员AoR = 40 mm,均为男性。在这个亚群中,在85年的随访中,主动脉尺寸增加(40.9 1.3至42.9 3.6 mm;p <0.01),其中包括3名前运动员,在没有症状或全身性疾病证据的情况下,在15-16年后aor扩张(达到50mm, 50mm和48mm)。结论:主动脉根部扩张(=40 mm)在训练有素的运动员中很少见,并不是“运动员心脏”的一贯特征。AoR =40 mm的运动员的纵向评估显示进一步的尺寸增加,偶尔非常明显。在这些运动员中,选择性地限制最激烈的竞技运动可以减少与主动脉加速扩张相关的风险。
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