Studies on the Analgesic Potential of leaf Extracts of Allium humile on Swiss albino mice

Abstract

Allium humile is a medicinal plant found at the Alpine Himalayas of Uttarakhand at altitute of 2500-3000 meters height of sea level. In India, Allium humile, is used by local people as a spice and in ethano-medicine. In the present study, Allium humile leaves were explored for their analgesic potential on experimental model and compared to standard drugs. Allium humile at the doses of 100 mg/kg and aspirin 25 mg/kg exhibited significant (p>0.05) inhibition of the control writhes at the rate of 64.25%, 44.54%, 44.54% and 59.89% respectively when compared to that of control. Thus, methanolic extract of the plant can be fully explored for its analgesic potential which has not been reported so far. The plant extract showed a relative low toxicity hence justifies the folkloric use of plant by the local people in Western Himalayan region for curing inflammation and painful conditions.