Wan-Kyu Lee, Hyeong-Jun Lim, S. Kim, H. Kimoto, S. Ohmomo, Y. Tashiro, H. Takebe
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引用次数: 16
Abstract
The effect of Lactococcus lactis subsp. lactis biovar diacetylactis N7 (LACC-N7) and Lactococcus lactis subsp. lactis 527 (LACC-527) strains isolated from dairy products on serum cholesterol levels in the SD rats were investigated. The administration of LACC-N7 significantly decreased total serum cholesterol (p<0.001) and triglycerides (p<0.05) and increased HDL-cholesterol ratio to total cholesterol (p<0.05) at 6 weeks post-administration. LACC-527 had an effect on total serum cholesterol (p<0.05) and HDL-cholesterol ratio to total cholesterol (p<0.05) at 6 weeks and triglycerides (p<0.01) at 4 weeks post-administration. Enterococcus faecium (ENT-1) also significantly decreased total serum cholesterol (p<0.001), and increased the HDL-cholesterol ratio to total cholesterol (p<0.05). These results suggest that LACC-N7 and LACC-527 would be effective as probiotics for the prevention of hypercholesterolemia and fatty liver.
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